Results 21 to 30 of about 46,526 (241)

Effect of calcium ionophore (A23187) on embryo development and its safety in PGT cycles

Frontiers in Endocrinology, 2023
BackgroundIntracytoplasmic sperm injection (ICSI) has tremendous advantages for resolving the problem of male infertility. However, ICSI fertilization can fail in some patients because of various reasons, primarily because of the failure of oocyte ...
Junya Zhang, Junya Zhang, Guidong Yao, Guidong Yao, Tongwei Zhang, Tongwei Zhang, Jingyi Hu, Jingyi Hu, Guang Yang, Guang Yang, Jiahuan He, Jiahuan He, Qina He, Qina He, Huiying Fan, Huiying Fan, Yucheng Bai, Yucheng Bai, Yingpu Sun, Yingpu Sun   +19 more
doaj   +1 more source

Can total fertilization failure be predicted in in vitro fertilization cycles?

Zdravniški Vestnik, 2011
Objective: To analyze predictors of the IVF cycles with high risk of total fertilization failure (TFF). Methods: A retrospective analysis of 981 consecutive stimulated IVF cycles with successful oocyte retrieval.
Ksenij Rakić, Veljko Vlaisavljević, Milan Reljič   +2 more
doaj   +1 more source

Calcium Ionophore (A23187) Rescues the Activation of Unfertilized Oocytes After Intracytoplasmic Sperm Injection and Chromosome Analysis of Blastocyst After Activation

Frontiers in Endocrinology, 2021
Calcium is a crucial factor in regulating the biological behavior of cells. The imbalance of calcium homeostasis in cytoplasm will cause abnormal behavior of cells and the occurrence of diseases.
Ziwen Xu, Ziwen Xu, Guidong Yao, Guidong Yao, Wenbin Niu, Wenbin Niu, Huiying Fan, Huiying Fan, Xueshan Ma, Xueshan Ma, Senlin Shi, Senlin Shi, Haixia Jin, Haixia Jin, Wenyan Song, Wenyan Song, Yingpu Sun, Yingpu Sun   +17 more
doaj   +1 more source

Identification of Novel Mutations in CDC20: Expanding the Mutational Spectrum for Female Infertility

Frontiers in Cell and Developmental Biology, 2021
Oocyte maturation and fertilization are fundamental processes for successful human reproduction, and abnormalities in these processes will cause infertility.
Lin Zhao, Lin Zhao, Yichun Guan, Qingxia Meng, Weijie Wang, Ling Wu, Biaobang Chen, Jijun Hu, Jiawei Zhu, Zhihua Zhang, Jian Mu, Yao Chen, Yiming Sun, Tianyu Wu, Wenjing Wang, Zhou Zhou, Jie Dong, Yang Zeng, Ruyi Liu, Qiaoli Li, Jing Du, Yanping Kuang, Qing Sang, Lei Wang   +23 more
doaj   +1 more source

Assisted Oocyte Activation following Intracytoplasmic Sperm Injection: A Sensible Option for Infertile Couples with Severe Teratozoospermia [PDF]

International Journal of Fertility and Sterility, 2023
The intracytoplasmic sperm injection (ICSI) has significantly improved male factor infertility treatment; however, complete fertilization failure still occurs in 1-5% of ICSI treatment cycles mainly due to oocyte activation failure.
Marziyeh Tavalaee, Nushin Naderi, Navid Esfandiari, Mohammad Hossein Nasr-Esfahani   +3 more
doaj   +1 more source

Homozygous Mutations in WEE2 Cause Fertilization Failure and Female Infertility [PDF]

American Journal of Human Genetics, 2018
Qing Sang, Yanping Kuang, Zhihua Zhang   +2 more
exaly   +2 more sources

Artificial oocyte activation using Ca2+ ionophores following intracytoplasmic sperm injection for low fertilization rate

Frontiers in Endocrinology, 2023
This large multi-center retrospective study examined whether artificial oocyte activation (AOA) using Ca2+ ionophore following ICSI improves the live birth rate for couples with previous ICSI cycles of unexplained low fertilization rate.
Kazuhiro Akashi, Mitsutoshi Yamada, Seung Chik Jwa, Hiroki Utsuno, Shintaro Kamijo, Yasushi Hirota, Mamoru Tanaka, Yutaka Osuga, Naoaki Kuji   +8 more
doaj   +1 more source

Prognosis of Congenital Anomalies in Conceptions Following In Vitro Fertilization: A Multicenter Retrospective Cohort Study in China

Frontiers in Endocrinology, 2022
BackgroundConceptions following in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) have an increased risk of congenital anomalies. Few studies have explored the prognosis of fetuses with congenital anomalies.
Jie Bao, Jie Bao, Jie Bao, Jie Bao, Lixue Chen, Lixue Chen, Lixue Chen, Lixue Chen, Yongxiu Hao, Yongxiu Hao, Yongxiu Hao, Yongxiu Hao, Hongping Wu, Hongping Wu, Hongping Wu, Hongping Wu, Xiaojin He, Chuncheng Lu, Xinhua Ji, Jie Qiao, Jie Qiao, Jie Qiao, Jie Qiao, Yuanyuan Wang, Yuanyuan Wang, Yuanyuan Wang, Yuanyuan Wang, Hongbin Chi, Hongbin Chi, Hongbin Chi, Hongbin Chi   +30 more
doaj   +1 more source

Fertilization failures and abnormal fertilization after intracytoplasmic sperm injection [PDF]

Human Reproduction, 1998
This study addresses the incidence of failed (0%) and suboptimal (50% fertilization in every cycle. Only 26% of the couples had 50% variation. The causes of failed and abnormal fertilization were studied in unfertilized and abnormally fertilized oocytes after staining with Hoechst 33342.
Flaherty, Sean P., Payne, Dianna, Matthews, Colin D.   +2 more
openaire   +2 more sources

Novel mutations in the PLCZ1 gene associated with human low or failed fertilization

Molecular Genetics & Genomic Medicine, 2020
Background Fertilization failure (FF) is a complex reproductive disorder characterized by the failure of pronuclei formation during fertilization. In addition to some cases caused by iatrogenic problems and known genetic factors, there are still many ...
Ping Yuan, Lingyan Zheng, Hao Liang, Qiyuan Lin, Songbang Ou, Yuqin Zhu, Luhua Lai, Qingxue Zhang, Zuyong He, Wenjun Wang   +9 more
doaj   +1 more source