Results 141 to 150 of about 2,639,951 (318)

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

Genome Editing Technologies to Improve Health‐Related Phytocompounds in Crops

open access: yesFood Frontiers, EarlyView.
ABSTRACT Due to rapid global population growth and the resulting significant increase in food demand, the world is facing an epidemic of malnutrition. Although yield improvement remains one of the main targets of breeding programs, much attention is being paid to the nutritional aspects of crops, including nutrients and bioactive compounds that are ...
Maria Dellino   +4 more
wiley   +1 more source

Anthocyanin Extracts From 11 Superfruits Mitigate Oxidative Stress and Inflammatory Damage in HK‐2 Cells Induced by Cadmium Exposure

open access: yesFood Frontiers, EarlyView.
ABSTRACT Cadmium (Cd) pollution has emerged as an escalating threat to human health, with its induced kidney toxicity being closely linked to oxidative stress and inflammation. In this study, we extracted and analyzed primary anthocyanins from 11 superfruits using UPLC‐Triple‐TOF/MS and evaluated their antioxidant capacity through DPPH, ABTS, FRAP, and
Jiaojiao Liang   +7 more
wiley   +1 more source

Harnessing Jasminum Bioactive Compounds: Updated Insights for Therapeutic and Food Preservation Innovations

open access: yesFood Frontiers, EarlyView.
Jasminum bioactives improve food preservation by providing antimicrobial and antioxidant effects, especially when incorporated into active packaging, edible films, and nanoformulations that enhance stability and controlled release. They also offer many pharmacological benefits, including anti‐inflammatory, neuroprotective, and wound‐healing properties.
Antonio Rescigno   +17 more
wiley   +1 more source

Multimodal Learning for Embryo Viability Prediction in Clinical IVF [PDF]

open access: yesarXiv
In clinical In-Vitro Fertilization (IVF), identifying the most viable embryo for transfer is important to increasing the likelihood of a successful pregnancy. Traditionally, this process involves embryologists manually assessing embryos' static morphological features at specific intervals using light microscopy.
arxiv  

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