Results 231 to 240 of about 282,360 (388)

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

New Perspectives on Polysaccharides From Gracilaria and Gracilariopsis (Rhodophyta) and Their Potential Applications in Future Industries

open access: yesFood Frontiers, EarlyView.
1. Gracilaria is abundantly available red seaweed that has been used as a traditional medicine and food for years and is rich in nutritional value. 2. Gracilaria polysaccharides are sulfated and have been reported to possess various beneficial biological activities and are widely used in food packaging, food formulation, cosmeceutical products, and ...
Amanda Tresiliana Mulio   +4 more
wiley   +1 more source

First live birth after <i>in vitro</i> fertilization in a woman with Alström syndrome: a case report. [PDF]

open access: yesFront Reprod Health
Carosso AR   +8 more
europepmc   +1 more source

Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation

open access: yesFood Frontiers, EarlyView.
PDIA4 is significantly upregulated in response to nutrient overload in pancreatic β‐cells, resulting in aberrant ROS production, β‐cell failure, and diabetes. PDIA4 facilitates cancer development by inhibiting caspase‐mediatedcell death in cancer and promoting VEGF‐mediated protumoral immunity andangiogenesis in the tumor microenvironment, highlighting
Yi‐San Lee   +4 more
wiley   +1 more source

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