Results 121 to 130 of about 182,992 (312)

Genetic Impacts on the Structure and Mechanics of Cellulose Made by Bacteria

open access: yesAdvanced Science, EarlyView.
A genetic mutation in a protease of a cellulose‐overproducing evolved bacterium significantly affects the proteome, structure, and mechanical properties of bio‐fabricated cellulose pellicles. By overexpressing synthase proteins that build the cellulose‐forming biological machinery of the cell, the evolved bacterium generates dense, stiff, and strong ...
Julie M. Laurent   +8 more
wiley   +1 more source

Co‐Selection of Low Cadmium Accumulation and High Yield During Tomato Improvement

open access: yesAdvanced Science, EarlyView.
This study finds that large‐fruited tomatoes accumulate less cadmium (Cd) compared to wild tomatoes and cherry tomatoes. This is because, during the improvement process of tomato, the low‐Cd allele LCT1A and the large fruit allele fw3.2T are closely linked, leading to a co‐selection event.
Xingyu Zhang   +11 more
wiley   +1 more source

Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene

open access: yesAdvanced Science, EarlyView.
Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan   +15 more
wiley   +1 more source

GmSop20 Functions as a Key Coordinator of the Oil‐To‐Protein Ratio in Soybean Seeds

open access: yesAdvanced Science, EarlyView.
This study investigates the seed oil‐to‐protein ratio as a comprehensive quality metric and identifies GmSop20 as a crucial regulatory gene through forward genetics methodologies. By integrating GmSop20 with superior haplotypes and using gene editing/overexpression, new strategies are provided for precisely tuning the seed oil‐to‐protein ratio, thereby
Haowei Zheng   +17 more
wiley   +1 more source

Tead1a Initiates Transcriptional Priming Through the TEAD1a/YAP‐Notch1‐Spi1/Cebpα Axis to Promote Neutrophil Fate

open access: yesAdvanced Science, EarlyView.
This study discovered that the protein TEAD1a is crucial for neutrophil development. In zebrafish models, disrupting TEAD1a or its interaction with partner protein YAP1 caused severe neutrophil deficiency. TEAD1a functions during the early HSC stage, activates Notch1 signaling in the GMP stage, and triggers Spi1 and Cebpα to drive neutrophil terminal ...
Wang Yiqin   +7 more
wiley   +1 more source

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