Genome Aging in Women: Hematopoietic Loss of X Chromosome as An Exemplar
As studies at the intersection of genetics and aging are rapidly advancing, genome aging provides a novel mechanism by which aging phenotypes occur. In this Review, the authors examine the rise, expansion, and the consequences of X chromosome loss in female blood cells.
Xihan Guo, Xueqin Dai
wiley +1 more source
Children with Fetal Alcohol Syndrome (FAS): 3D-Analysis of Palatal Depth and 3D-Metric Facial Length. [PDF]
Blanck-Lubarsch M +4 more
europepmc +1 more source
The use of deidentified organ donor testes for research
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source
Two case reports of fetal alcohol syndrome: broadening into the spectrum of cardiac disease to personalize and to improve clinical assessment. [PDF]
Onesimo R +7 more
europepmc +1 more source
In 22 066 first‐trimester pregnancies from six Chinese hospitals, biomarker measurements required recalibration to align with the established risk model. Continuous quality assurance is essential to ensure accurate preeclampsia risk assessment when implementing combined screening in new populations.
Jiao Liu +16 more
wiley +1 more source
Recognition of clinical characteristics for population-based surveillance of fetal alcohol syndrome. [PDF]
Andrews JG +8 more
europepmc +1 more source
ABSTRACT Objectives Polycythemia Vera (PV) is characterized by overproduction of erythrocytes, leading to a hypercoagulable state. Evidence regarding associations between PV and pregnancy outcomes is limited. The aim of our study was to provide robust evidence regarding the prevalence of pregnancy complications in women with PV.
Noah Margolese +5 more
wiley +1 more source
Immune Consequences of Metabolic Syndrome and Its Treatment: A Cytokine Perspective
Peripheral blood mononuclear cells (PBMCs) from individuals with metabolic syndrome (MetS) who were not using glucose‐and/or lipid lowering medication (GLLM) exhibited a broader cytokine production profile after in vitro antigen‐specific stimulation than PBMCs from individuals with MetS using such medications and from healthy donors.
Isabela Ghetti Macedo Isaac +7 more
wiley +1 more source
Changes in External Developmental Assets Across Adolescence in Low‐Income Urban Youth
ABSTRACT This study investigated longitudinal changes in external developmental assets (EDA)—support, empowerment, boundaries & expectations across ecological and interpersonal contexts of family, peers, school, and neighborhood—among predominantly Black, low‐income urban adolescents. A birth cohort of 367 adolescents (47% male) was assessed at ages 12,
Meeyoung O. Min +3 more
wiley +1 more source
Atypical fetal development: Fetal alcohol syndrome, nutritional deprivation, teratogens, and risk for neurodevelopmental disorders and psychopathology. [PDF]
Georgieff MK, Tran PV, Carlson ES.
europepmc +1 more source

