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The Early Developmental Outcomes of Prenatal Alcohol Exposure: A Review [PDF]

Frontiers in Neurology, 2018
Aim: This paper systematically reviews the literature on the effects of prenatal alcohol exposure on early child development from birth to 5 years with the aim to synthesize the developmental outcomes associated with prenatal alcohol exposure, and inform
Sivenesi Subramoney, Emma Eastman, Colleen Adnams, Dan J. Stein, Dan J. Stein, Kirsten A. Donald   +5 more
doaj   +4 more sources

Neurodevelopmental Trajectories Following Prenatal Alcohol Exposure [PDF]

Frontiers in Human Neuroscience, 2022
Prenatal alcohol exposure (PAE) interferes with neurodevelopment. The brain is particularly susceptible to the adverse consequences of prenatal alcohol exposure, and numerous studies have documented changes to brain anatomy and function, as well as ...
Eileen M. Moore, Yingjing Xia
doaj   +3 more sources

Mechanisms Underlying Cognitive Impairment Induced by Prenatal Alcohol Exposure

Brain Sciences, 2022
Alcohol is one of the most commonly used illicit substances among pregnant women. Clinical and experimental studies have revealed that prenatal alcohol exposure affects fetal brain development and ultimately results in the persistent impairment of the ...
Ahmad Alhowail
doaj   +3 more sources

NGF and BDNF Alterations by Prenatal Alcohol Exposure [PDF]

Current Neuropharmacology, 2019
Background: It is now widely established that the devastating effects of prenatal alcohol exposure on the embryo and fetus development cause marked cognitive and neurobiological deficits in the newborns. The negative effects of the gestational alcohol use have been well documented and known for some time.
Giampiero Ferraguti, Marco Fiore, Roberto Coccurello   +2 more
exaly   +5 more sources

Prenatal Alcohol Exposure as a Potential Contributor to Hydranencephaly: Clinical and Neurodevelopmental Perspectives [PDF]

Clinical Case Reports
Hydranencephaly is traditionally attributed to prenatal vascular disruption; however, chronic prenatal alcohol exposure may contribute through neurotoxicity, placental dysfunction, oxidative stress, and vascular injury.
Chukwuka Elendu, Botiwuoluwa M. Ogunmola, Adetokunbo A. Adesina, Alexandra U. Akudolu, Favour K. Mbakwe   +4 more
doaj   +2 more sources

Birth Defects Associated with Prenatal Alcohol Exposure—A Review

Children, 2023
Since the recognition of fetal alcohol syndrome, alcohol has been accepted as a human teratogen. However, little is known about the relation between prenatal alcohol exposure and the spectrum of associated major birth defects.
Katarzyna Anna Dyląg, Florencia Anunziata, Gretchen Bandoli, Christina Chambers   +3 more
doaj   +5 more sources

Relationships between Head Circumference, Brain Volume and Cognition in Children with Prenatal Alcohol Exposure. [PDF]

PLoS ONE, 2016
Head circumference is used together with other measures as a proxy for central nervous system damage in the diagnosis of fetal alcohol spectrum disorders, yet the relationship between head circumference and brain volume has not been investigated in this ...
Sarah Treit, Dongming Zhou, Albert E Chudley, Gail Andrew, Carmen Rasmussen, Sarah M Nikkel, Dawa Samdup, Ana Hanlon-Dearman, Christine Loock, Christian Beaulieu   +9 more
doaj   +1 more source

Concurrent nicotine exposure to prenatal alcohol consumption alters the hippocampal and cortical neurotoxicity

Heliyon, 2020
Aims: This study investigated the neurotoxic effects of prenatal alcohol and nicotine exposure in the cortex and hippocampus of rodents. Main methods: Behavioral alterations, electrophysiological changes, and biochemical markers associated with ...
Dwipayan Bhattacharya, Ayaka Fujihashi, Mohammed Majrashi, Jenna Bloemer, Subhrajit Bhattacharya, Manal Buabeid, Martha Escobar, Timothy Moore, Vishnu Suppiramaniam, Muralikrishnan Dhanasekaran   +9 more
doaj   +1 more source

Intersection of Epigenetic and Immune Alterations: Implications for Fetal Alcohol Spectrum Disorder and Mental Health

Frontiers in Neuroscience, 2021
Prenatal alcohol exposure can impact virtually all body systems, resulting in a host of structural, neurocognitive, and behavioral abnormalities. Among the adverse impacts associated with prenatal alcohol exposure are alterations in immune function ...
Alexandre A. Lussier, Alexandre A. Lussier, Alexandre A. Lussier, Tamara S. Bodnar, Joanne Weinberg   +4 more
doaj   +1 more source

Prenatal Alcohol Exposure as a Case of Involuntary Early Onset of Alcohol Use: Consequences and Proposed Mechanisms From Animal Studies

Frontiers in Behavioral Neuroscience, 2020
Prenatal alcohol exposure has been found to be an important factor determining later consumption of this drug. In humans, despite the considerable diversity of variables that might influence alcohol consumption, longitudinal studies show that maternal ...
Mirari Gaztañaga, Asier Angulo-Alcalde, M. Gabriela Chotro   +2 more
doaj   +1 more source