Results 1 to 10 of about 130,928 (302)
Background Sleep disturbances are frequently reported in children with autism spectrum disorder (ASD) and are associated with the severity of co-occurring symptoms.
Shirley Solomon +8 more
doaj +1 more source
Epigenetic Effects of Polybrominated Diphenyl Ethers on Human Health. [PDF]
Disruption of epigenetic regulation by environmental toxins is an emerging area of focus for understanding the latter's impact on human health. Polybrominated diphenyl ethers (PBDEs), one such group of toxins, are an environmentally pervasive class of ...
Poston, Robert G, Saha, Ramendra N
core +1 more source
Bi-allelic GAD1 variants cause a neonatal onset syndromic developmental and epileptic encephalopathy. [PDF]
Developmental and epileptic encephalopathies are a heterogeneous group of early-onset epilepsy syndromes dramatically impairing neurodevelopment. Modern genomic technologies have revealed a number of monogenic origins and opened the door to therapeutic ...
Alix, E +30 more
core +2 more sources
Background: Adolescents with inflammatory bowel disease (IBD) are faced with the complexities of acquiring self-management behaviours at a time when they are also navigating developmental challenges associated with adolescence. To date, limited treatment
Cassandra Screti +4 more
doaj +1 more source
Patient-derived iPSCs show premature neural differentiation and neuron type-specific phenotypes relevant to neurodevelopment. [PDF]
Ras/MAPK pathway signaling is a major participant in neurodevelopment, and evidence suggests that BRAF, a key Ras signal mediator, influences human behavior.
Camacho, FM +10 more
core
Exaggerated CpH methylation in the autism-affected brain. [PDF]
BackgroundThe etiology of autism, a complex, heritable, neurodevelopmental disorder, remains largely unexplained. Given the unexplained risk and recent evidence supporting a role for epigenetic mechanisms in the development of autism, we explored the ...
Arking, Dan E +4 more
core +1 more source
Reliably quantifying the severity of social symptoms in children with autism using ASDSpeech
Several studies have demonstrated that the severity of social communication problems, a core symptom of Autism Spectrum Disorder (ASD), is correlated with specific speech characteristics of ASD individuals.
Marina Eni +7 more
doaj +1 more source
Emotional eating (EE; defined as overeating irrespective of satiety and in response to emotional states) develops within childhood, persists into adulthood, and is linked with obesity.
Rebecca A. Stone +3 more
doaj +1 more source
Transcriptional Profiles for Glutamate Transporters Reveal Differences Between Organophosphates but Similarities with Unrelated Neurotoxicants [PDF]
The developmental neurotoxicity of organophosphates involves mechanisms other than their shared property as cholinesterase inhibitors, among which are excitotoxicity and oxidative stress.
Lobner, Doug +2 more
core +2 more sources
Puzzling Out Neurodevelopment [PDF]
To understand an immensely complex process such as the development of the brain, it’s often easier to start small and think about simpler questions contained within the massive whole. With this in mind, we are happy to share with you a series of Reviews designed to do just this—discuss a collection of diverse topics within the larger scope of ...
openaire +2 more sources

