Results 1 to 10 of about 1,533 (117)

Estimated incidence and number of new cases with prenatal alcohol exposure and fetal alcohol spectrum disorders in Finland 1990-2025. [PDF]

PLoS ONE
BackgroundFetal alcohol spectrum disorders (FASD) arising from prenatal alcohol exposure (PAE) are the leading preventable cause of neurobehavioral disorders. Early pregnancy is particularly vulnerable to ethanol toxicity, yet alcohol use often continues
Mirjami Jolma, Mikko Koivu-Jolma, Mika Gissler, Anne Sarajuuri, Ilona Autti-Rämö   +4 more
doaj   +2 more sources

From teratogens to trajectories: Integrating teratology and Developmental Origins of Health and Disease (DOHaD) frameworks for a new take on fetal alcohol spectrum disorders (FASD) [PDF]

Neurobiology of Stress
Research on the effects of prenatal alcohol exposure (PAE) developed within two research frameworks that progressed largely in parallel. Classical teratology was the dominant framework for many years, focusing on prenatal exposure to toxic agents that ...
Joanne Weinberg, Karen Moritz
doaj   +2 more sources

Oral and written communication skills of adolescents with prenatal alcohol exposure (PAE) compared with those with no/low PAE: A systematic review. [PDF]

Int J Lang Commun Disord, 2021
Kippin NR, Leitão S, Watkins R, Finlay-Jones A.   +3 more
europepmc   +2 more sources

The effect of prenatal alcohol exposure (PAE) on the onset of speech disorders and communication problems in children and adolescents

Journal of Education, Health and Sport, 2022
Alcohol consumption has many negative effects on the human body, and has been proven to have teratogenic effects on fetal development. Prenatal alcohol exposure (PAE) is associated with growth deficits and neurodevelopmental disorders, including fetal ...
Anna Gryc, Jakub Lipiec, Monika Grudzień, Jagna Golemo, Rafał Świdziński   +4 more
doaj   +1 more source

Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure

Cell Reports, 2023
Summary: Structural and functional deficits in brain connectivity are reported in patients with fetal alcohol spectrum disorders (FASDs), but whether and how prenatal alcohol exposure (PAE) affects axonal development of neurons and disrupts wiring ...
Mike Altounian, Anaïs Bellon, Fanny Mann   +2 more
doaj   +1 more source

Decreased resting-state alpha peak frequency in children and adolescents with fetal alcohol spectrum disorders or prenatal alcohol exposure

Developmental Cognitive Neuroscience, 2022
Prenatal alcohol exposure (PAE) can result in long-lasting changes to physical, behavioral, and cognitive functioning in children. PAE might result in decreased white matter integrity, corticothalamic tract integrity, and alpha cortical oscillations ...
Felicha T. Candelaria-Cook, Megan E. Schendel, Lucinda Flynn, Cassandra Cerros, Piyadasa Kodituwakku, Ludmila N. Bakhireva, Dina E. Hill, Julia M. Stephen   +7 more
doaj   +1 more source

Alcohol exposure before and during pregnancy is associated with reduced fetal growth: the Safe Passage Study

BMC Medicine, 2023
Background Prenatal alcohol exposure (PAE) is a worldwide public health concern. While PAE is known to be associated with low birth weight, little is known about timing and quantity of PAE on fetal growth.
Marin Pielage, Hanan El Marroun, Hein J. Odendaal, Sten P. Willemsen, Manon H. J. Hillegers, Eric A. P. Steegers, Melek Rousian   +6 more
doaj   +1 more source

Microbiota and nutrition as risk and resiliency factors following prenatal alcohol exposure

Frontiers in Neuroscience, 2023
Alcohol exposure in adulthood can result in inflammation, malnutrition, and altered gastroenteric microbiota, which may disrupt efficient nutrient extraction.
Deepa Upreti, Siara K. Rouzer, Abigail Bowring, Emma Labbe, Rosaline Kumar, Rajesh C. Miranda, Amanda H. Mahnke   +6 more
doaj   +1 more source

Prenatal alcohol exposure alters mRNA expression for stress peptides, glucocorticoid receptor function and immune factors in acutely stressed neonatal brain

Frontiers in Neuroscience, 2023
BackgroundThe amygdala, hippocampus and hypothalamus are critical stress regulatory areas that undergo functional maturation for stress responding initially established during gestational and early postnatal brain development.
Chaselyn D. Ruffaner-Hanson, Annette K. Fernandez-Oropeza, Melody S. Sun, Kevin K. Caldwell, Andrea M. Allan, Daniel D. Savage, C. Fernando Valenzuela, Shahani Noor, Erin D. Milligan   +8 more
doaj   +1 more source

Modulatory role of prenatal alcohol exposure and adolescent stress on the response to arthritis challenge in adult female rats

EBioMedicine, 2022
Summary: Background: There are known environmental risk factors associated with rheumatoid arthritis; however, less is known regarding how the prenatal environment impacts later-life risk for rheumatoid arthritis.
Tamara S. Bodnar, David Y. Mak, Lesley A. Hill, Linda Ellis, Wayne Yu, Joanne Weinberg   +5 more
doaj   +1 more source