Results 31 to 40 of about 72,912 (288)

Successful Management of the Fetal Severe Anemia Associated with Jra Alloimmunization by Intrauterine Transfusion of Jr(a+) Red Blood Cells

open access: yesCase Reports in Obstetrics and Gynecology, 2019
Objective. We present a case of fetal severe anemia associated with Jra alloimmunization, which was managed using Doppler measurement of the peak systolic velocity of the fetal middle cerebral artery (MCA-PSV) and intrauterine transfusion (IUT) of Jr(a+)
Masatake Toshimitsu   +4 more
doaj   +1 more source

Fetal anemia and heart rate patterns [PDF]

open access: yesJournal of Perinatal Medicine, 1982
A retrospective survey was performed of the clinical records and cardiotocograms (CTG) of fetuses born in 1978 and 1979 at Helsinki University Central Hospital with hemoglobin concentration less than 170 g/liter in peripheral blood or umbilical artery. Eighty-three fetuses (0.7%) had thus defined anemia.
openaire   +3 more sources

Nonimmune hydrops fetalis due to autosomal recessive hereditary spherocytosis

open access: yesCase Reports in Women's Health, 2017
Background: Hereditary spherocytosis is the most common form of inherited hemolytic anemia and is characterized by a structural defect in the RBC membrane.
Dawn M. Hannah   +2 more
doaj   +1 more source

Fetal hemoglobin in sickle cell anemia

open access: yesBlood, 2011
AbstractFetal hemoglobin (HbF) is the major genetic modulator of the hematologic and clinical features of sickle cell disease, an effect mediated by its exclusion from the sickle hemoglobin polymer. Fetal hemoglobin genes are genetically regulated, and the level of HbF and its distribution among sickle erythrocytes is highly variable.
Idowu, Akinsheye   +7 more
openaire   +3 more sources

Diagnosis of Severe Fetal Anemia Based on Perinatal Outcomes: A Comparative Analysis of the Current Reference Values

open access: yesAnemia, 2013
Objectives. To compare current criteria for severe fetal anemia diagnosis. Methodology. A cohort study analyzed 105 alloimmunized fetuses that underwent cordocentesis due to risk of anemia.
Zilma Silveira Nogueira Reis   +5 more
doaj   +1 more source

Ultrasound evidence of early fetal growth restriction after maternal malaria infection.

open access: yes, 2012
BACKGROUND: Intermittent preventive treatment (IPT), the main strategy to prevent malaria and reduce anaemia and low birthweight, focuses on the second half of pregnancy. However, intrauterine growth restriction may occur earlier in pregnancy. The aim of
Papageorghiou Aris T.   +42 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Prenatal treatment of severe fetal hemolytic disease due to anti-M alloimmunization by serial intrauterine transfusions

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2017
Objective: Fetal hemolytic disease is a common cause of fetal hydrops and fetal morbidity and mortality. Despite its relatively low frequency, the anti-M IgG antibody is one of the causes of severe fetal anemia and intrauterine death; only a few cases ...
Lin Li   +4 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

The association of parasitic infections in pregnancy and maternal and fetal anemia: a cohort study in coastal Kenya.

open access: yesPLoS Neglected Tropical Diseases, 2014
BackgroundRelative contribution of these infections on anemia in pregnancy is not certain. While measures to protect pregnant women against malaria have been scaling up, interventions against helminthes have received much less attention.
Elizabeth M McClure   +8 more
doaj   +1 more source

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