Results 41 to 50 of about 14,391 (256)

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Case report: Prenatal diagnosis of fetal non-compaction cardiomyopathy with bradycardia accompanied by de novo CALM2 mutation

Frontiers in Pediatrics, 2022
We herein report what appears to be the first case of fetal non-compaction cardiomyopathy in both ventricles accompanied by a mutation in the calmodulin gene (CALM2).
Wen Zhang, Wen Zhang, Xiaohui Dai, Xiaohui Dai, Hanmin Liu, Hanmin Liu, Lei Li, Lei Li, Shu Zhou, Shu Zhou, Qi Zhu, Qi Zhu, Jiao Chen, Jiao Chen   +13 more
doaj   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Accurate Fetal QRS-Complex Classification from Abdominal Electrocardiogram Using Deep Learning

International Journal of Computational Intelligence Systems, 2023
Fetal heart monitoring during pregnancy plays a critical role in diagnosing congenital heart disease (CHD). A noninvasive fetal electrocardiogram (fECG) provides additional clinical information for fetal heart monitoring.
Annisa Darmawahyuni, Bambang Tutuko, Siti Nurmaini, Muhammad Naufal Rachmatullah, Muhammad Ardiansyah, Firdaus Firdaus, Ade Iriani Sapitri, Anggun Islami   +7 more
doaj   +1 more source

Atrial fibrillation with rapid ventricular response as a maternal presentation of mirror syndrome: a case report

Case Reports in Women's Health, 2022
Mirror syndrome is the phenomenon of fetal hydrops causing maternal edema and weight gain. Here, we report a case of arrhythmia as the primary maternal symptom.A 36-year-old woman, G2P1001, at 34.5 weeks of gestation presented with new-onset fetal ...
Elena HogenEsch, Carly Dahl, Alexander Samworth, Seema Venkatachalam, Priya Rajan, Elizabeth M.S. Lange   +5 more
doaj   +1 more source

An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring

Advanced Science, EarlyView.
This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal, Kai‐Po Fan, Sheng‐Chun Hung, Jaba Roy Chowdhury, Jun‐Hsun Chung, Meenakshi Ray, Hsiang‐Yun Hsu, Fu‐Cheng Kao, Kuei‐Lin Liu, Zong‐Hong Lin   +9 more
wiley   +1 more source

Fetal Supraventricular Tachycardia: What the Adult Cardiologist Needs to Know

, 2022
Fetal supraventricular tachycardia management is challenging, with consequences for both the fetus and the mother. If left untreated, fetal hydrops may ensue, at which point delivery and treatment of the arrhythmia is preferred.
Lau, Joe F., Wolfe, Diana S., Sutopa Purkayastha, Anna E. Bortnick, Joao D. Fontes, Joe F. Lau, Fontes, Joao, Michael Weinreich, Diana S. Wolfe, Bortnick, Anna E., Purkayastha, Sutopa, Weinreich, Michael   +11 more
core   +2 more sources

Auscultation of fetal cardiac arrhythmia: A clue in the prenatal diagnosis of trisomy 18

, 1981
A case is described in which the obstetrician was alerted to the possibility of a congenital malformation by hearing fetal cardiac arrhythmia. The correct management of the delivery depended upon antenatal establishment of fetal karyotype, which revealed
Van Regemoorter, N., Rodesch, Frédéric, Leleux, D., Picard, Claude, Vamos, Eszter   +4 more
core   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Fetal arrhythmias: Surveillance and management

Hellenic Journal of Cardiology, 2019
Fetal arrhythmias warrant sophisticated surveillance and management, especially for the high-risk pregnancies. Clinically, fetal arrhythmias can be categorized into 3 types: premature contractions, tachyarrhythmias, and bradyarrhythmias.
Shi-Min Yuan
doaj   +1 more source