Results 71 to 80 of about 1,005,499 (350)

Measurement of Androgen and Estrogen Concentrations in Cord Blood: Accuracy, Biological Interpretation and Applications to Understanding Human Behavioural Development

Frontiers in Endocrinology, 2014
Accurately measuring hormone exposure during prenatal life presents a methodological challenge and there is currently no ‘gold standard’ approach. Ideally, circulating fetal hormone levels would be measured at repeated time points during pregnancy ...
Lauren P Hollier, Lauren P Hollier, Jeffrey A Keelan, Martha eHickey, Murray T Maybery, Andrew J.O. Whitehouse   +5 more
doaj   +1 more source

Effectiveness of fetal scalp stimulation test in assessing fetal wellbeing during labor, a retrospective cohort study

BMC Pregnancy and Childbirth, 2020
Background It is discussed whether fetal scalp stimulation (FSS) test is a reliable complimentary tool to cardiotocography (CTG) to assess fetal wellbeing during labor.
Farzaneh Shakouri, Linda Iorizzo, Hellen Mc Kinnon Edwards, Christina Anne Vinter, Karl Kristensen, Per-Erik Isberg, Nana Wiberg   +6 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Routine Fetal Rhd Genotyping with Maternal Plasma: A Four-Year Experience in Belgium [PDF]

, 2008
peer reviewedBACKGROUND: The objective was to evaluate the diagnostic value of RHD fetal genotyping from the plasma of D- mothers as soon as 10 weeks' gestation in a routine clinical practice in Belgium.
Bianchi DW, Colin Y, Cortey A, Daniels G, Flegel WA, Flegel WA, Grootkerk MG, Judd WJ, Legler J, Mannessier L, Minon JM, Moise KJ, Moise KJ, Singleton BK, Wagner FF, Wagner FF   +15 more
core   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Hemorragia fetomaterna masiva con patrón cardiotocográfico sinusoidal: Presentación de un caso y revisión de la literatura Massive fetomaternal hemorrhage with cardiotocographic sinusoidal rhythm: A case presentation and literature review

Revista Colombiana de Obstetricia y Ginecología, 2011
Introducción: la transfusión fetomaterna masiva (TFM) es una entidad con una elevada morbilidad y mortalidad fetal, suele cursar con una disminución en la percepción de los movimientos fetales por parte de la madre, y la presencia de un patrón ...
Daniel Abehsera-Davó, Carlos Iglesias-Sánchez, Fernando Magdaleno Dans, Antonio González-González   +3 more
doaj  

Androgen levels in the fetal cord blood of children born to women with polycystic ovary syndrome: a meta-analysis [PDF]

, 2020
Chang-Ling Duan, Tianjiao Pei, Yujing Li, Qi Cao, Hanxiao Chen, Jing Fu   +5 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source