Results 261 to 270 of about 1,402,097 (359)

Early hemodynamic changes after fetal aortic stenosis valvuloplasty predict biventricular circulation at birth

, 2018
Aaron R. Prosnitz, Monika Drogosz, Audrey C. Marshall, Louise Wilkins‐Haug, Carol B. Benson, Lynn A. Sleeper, Wayne Tworetzky, Kevin G. Friedman   +7 more
openalex   +2 more sources

Nanoparticle Adjuvant Design Enhances Germinal Center Responses Targeting Conserved Subdominant Epitopes for Pan‐Coronavirus Vaccine Development

Advanced Science, EarlyView.
Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang, Kanella M. Cohen, Liqiang Chen, Xiaowo Kang, Chang Liu, Megan E. Demouth, Wenxia Jiang, Alexander R. Maldeney, Rong Tong, Zunlong Ke, Kartik Chandran, Wei Luo, Qian Yin   +12 more
wiley   +1 more source

Following the flow: in vivo imaging of fetal foramen ovale physiology using four-dimensional flow magnetic resonance imaging with doppler ultrasound gating. [PDF]

Radiol Case Rep
Gerstner Saucedo J, Fujiwara T, Englund EK, Park S, Friesen R, Browne LP, Barker AJ.   +6 more
europepmc   +1 more source

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

Advanced Science, EarlyView.
In this work, we showcased two significant scientific advances in (i) developing a portable biosensor technology for rapid decentralized prostate cancer urinary biomarker testing and reporting, with superior performance to current clinical testing practice; and (ii) proposing a clinical validation framework (for our biosensor development) which can be ...
Kevin M. Koo, Grant Phillips, Sriganesh Srihari, Áine Farrell, Binny Jaradi, Kira J. Fitzpatrick, John W. Yaxley, Hemamali Samaratunga, Paul N. Mainwaring, Ke‐lin Ru, Darren J. Korbie, Scott A. Tomlins, Matthew J. Roberts, Robert A. Gardiner, Matt Trau   +14 more
wiley   +1 more source

Fetal posterior cerebral artery infarction due to carotid dissection: a case report. [PDF]

J Med Case Rep
Majoul MS, Ben Lakhal A, Ben Mohamed D, Nagi S, Ben Sassi S.   +4 more
europepmc   +1 more source

A Multiscale Mathematical Model for the Fetal Blood Circulation of the Second Half of Pregnancy [PDF]

Bettine G. van Willigen, M. Beatrijs van der Hout‐van der Jagt, Peter H. M. Bovendeerd, Wouter Huberts, Frans N. van de Vosse   +4 more
openalex   +1 more source

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

Advanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu, Jiaxin Zhang, Xiangyu Yan, Nuo Li, Yu‐Chao Dong, Zihao Wang, Daowei Li, Yong Du, Huan Wang   +8 more
wiley   +1 more source

Targeted nanoparticles for placenta-specific drug delivery in pregnant rhesus macaques. [PDF]

Theranostics
Schmidt JK, Mitzey AM, Keding LT, Shaw SA, Renshall L, Beards F, Al-Mugotir MH, Simmons HA, Basu P, Schotzko ML, Ren E, Golos TG, Harris LK.   +12 more
europepmc   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Fetal circulation (diagram)

, 2020
openaire   +1 more source