Results 51 to 60 of about 938,719 (314)

Association between gestational weight gain and chronic disease risks in later life

Scientific Reports
To assess the association between gestational weight gain (GWG) and the risk of developing chronic diseases in later life, this historical cohort study of 318 non-overweight women was conducted between April 2017 and November 2020 at a hospital in Tokyo.
Yuki Kamihara, Kohei Ogawa, Naho Morisaki, Naoko Arata, Seiji Wada   +4 more
doaj   +1 more source

Fetal liver blood flow distribution: role in human developmental strategy to prioritize fat deposition versus brain development

, 2012
Among primates, human neonates have the largest brains but also the highest proportion of body fat. If placental nutrient supply is limited, the fetus faces a dilemma: should resources be allocated to brain growth, or to fat deposition for use as a ...
Crozier, SR, Sarah R. Crozier, Sian M. Robinson, Guttorm Haugen (141243), Sarah R Crozier, Kiserud, T., Hanson, M.A., Inskip, H.M., Haugen Guttorm, Nicholas C. W. Harvey, Harvey Nicholas C. W., Crozier Sarah R., Haugen, G., Hazel M. Inskip, Robinson Sian M., Crozier, S.R., Inskip, HM, Mark A. Hanson (114427), Cyrus Cooper (141250), Godfrey, Keith M., Sian M Robinson, Mark A Hanson, Cyrus Cooper, Cooper Cyrus, Lucy Davies, Harvey, NC, Hazel M. Inskip (141248), Haugen, G, Guttorm Haugen, Harvey, N.C., Godfrey Keith M., Kiserud, T, Robinson, S.M., Mark A. Hanson, Keith M Godfrey, Nicholas C W Harvey, Hanson Mark A., Torvid Kiserud, Southampton Women's Survey Study Group, Cooper, Cyrus, Davies, L, Hanson, MA, Sarah R. Crozier (141254), Keith M. Godfrey, Inskip Hazel M., Godfrey, KM, Hazel M Inskip, Sian M. Robinson (141258), Kiserud Torvid, Keith M. Godfrey (141238), Cooper, C., Robinson, SM, Davies Lucy, Cooper, C, Torvid Kiserud (141246), Lucy Davies (141261), Davies, L., Nicholas C. W. Harvey (141252)   +57 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Animal models of fetal growth restriction: Considerations for translational medicine.

, 2015
Fetal growth restriction (FGR) is the failure of a fetus to reach its full genetic growth potential. It occurs in up to 8% of pregnancies, and after premature birth is the second leading cause of infant mortality and morbidity.
David, AL, Swanson, AM, David, A.L., Swanson, A.M.   +3 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Development of the human fetal thyroid

General and Comparative Endocrinology, 1968
Abstract The human fetal thyroid between the 65–80 mm crown-rump stage (73–80 gestational days) attains maturity in terms of relative weight, appearance of colloid containing central cavities, and ability to produce iodinated organic products, including thyroxine.
openaire   +2 more sources

Cellular and hormonal disruption of fetal testis development in sheep reared on pasture treated with sewage sludge

, 2005
The purpose of this study was to evaluate whether experimental exposure of pregnant sheep to a mixture of environmental chemicals added to pasture as sewage sludge (n = 9 treated animals) exerted effects on fetal testis development or function ...
Paul, Catriona, Kyle, Carol E, McKinnell, Chris, Sharpe, Richard M, Catriona Paul, Richard M. Sharpe, Hayley Scott, Chris McKinnell, Scott, Hayley, Rhind, Stewart M, Carol E. Kyle, Stewart M. Rhind   +11 more
core   +1 more source

Elevated fetal steroidogenic activity in autism [PDF]

, 2015
Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor.
Cohen, A. S., Melgaard, L, Melgaard, L., M W Abdallah, Abdallah, M. W., D M Hougaard, Hougaard, D M, S Baron-Cohen, Baron-Cohen, S., M V Lombardo, B Auyeung, Auyeung, B., Ruta, L., B Chakrabarti, L Melgaard, Auyeung, B; id_orcid, Chakrabarti, Bhisma, Lombardo, M V, Nørgaard-Pedersen, B., B Nørgaard-Pedersen, A S Cohen, Abdallah, M W, Nørgaard-Pedersen, B, Ruta, L, Lombardo, M. V., Baron-Cohen, S, Chakrabarti, B, L Ruta, Cohen, A S, Hougaard, D. M.   +29 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Association between the cumulative duration of abnormal cardiotocography patterns and fetal acidemia

The Journal of Maternal-Fetal & Neonatal Medicine
Objective To assess the association between the cumulative duration of abnormal cardiotocography (CTG) findings, classified using the Japan Society of Obstetrics and Gynecology (JSOG) five-tier cardiotocography (CTG) classification system, and fetal ...
Kazuhiro Kajiwara, Kohei Ogawa, Ohara Reiko, Nagayoshi Umehara, Akutsu Hidenori, Aikou Okamoto, Seiji Wada   +6 more
doaj   +1 more source