Results 51 to 60 of about 15,951,746 (312)

Financing the Future with the IDB Group [PDF]

open access: yes, 2019
Mobilizing resources is critical to the implementation of the 2030 Agenda and multilateral development banks in particular have been called upon to crowd-in additional financing for the Sustainable Development Goals (SDGs).
Inter-American Development Bank
core   +1 more source

The IDB Group and the Sustainable Development Goals [PDF]

open access: yes, 2022
The IDB Group is committed to supporting countries in Latin America and the Caribbean accelerating progress toward the Sustainable Development Goals.
Inter-American Development Bank
core   +1 more source

Association between gestational weight gain and chronic disease risks in later life

open access: yesScientific Reports
To assess the association between gestational weight gain (GWG) and the risk of developing chronic diseases in later life, this historical cohort study of 318 non-overweight women was conducted between April 2017 and November 2020 at a hospital in Tokyo.
Yuki Kamihara   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Association between the cumulative duration of abnormal cardiotocography patterns and fetal acidemia

open access: yesThe Journal of Maternal-Fetal & Neonatal Medicine
Objective To assess the association between the cumulative duration of abnormal cardiotocography (CTG) findings, classified using the Japan Society of Obstetrics and Gynecology (JSOG) five-tier cardiotocography (CTG) classification system, and fetal ...
Kazuhiro Kajiwara   +6 more
doaj   +1 more source

Development of the human fetal thyroid

open access: yesGeneral and Comparative Endocrinology, 1968
Abstract The human fetal thyroid between the 65–80 mm crown-rump stage (73–80 gestational days) attains maturity in terms of relative weight, appearance of colloid containing central cavities, and ability to produce iodinated organic products, including thyroxine.
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Association between very advanced maternal age and adverse pregnancy outcomes: a cross sectional Japanese study

open access: yesBMC Pregnancy and Childbirth, 2017
Background While several studies have demonstrated the increased risk of pregnancy complications for women of advanced age, few studies have focused on women with very advanced age (≥ 45), despite the increasing rate of pregnancy among such women ...
Kohei Ogawa   +6 more
doaj   +1 more source

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