Results 101 to 110 of about 9,953,634 (331)
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Pregnancy in Women with Cardiovascular Diseases.
Methodist DeBakey Cardiovascular Journal, 2017 Patients with cardiovascular disease represent a significant cohort at risk for complications during pregnancy. The normal physiologic changes of pregnancy could further compromise the hemodynamics of various cardiovascular conditions, resulting in ...
Karolina Adam
semanticscholar +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Cortical folding alterations in fetuses with isolated non-severe ventriculomegaly
NeuroImage: Clinical, 2018 Neuroimaging of brain diseases plays a crucial role in understanding brain abnormalities and early diagnosis. Of great importance is the study of brain abnormalities in utero and the assessment of deviations in case of maldevelopment. In this work, brain
Oualid M. Benkarim +6 more
doaj
Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source
The Fetal Origins of the Metabolic Syndrome: Can We Intervene?
Journal of Pregnancy, 2012 Epidemiological studies have suggested that metabolic programming begins during fetal life and adverse events in utero are a critical factor in the etiology of chronic diseases and overall health.
Noelle Ma, Daniel B. Hardy
doaj +1 more source
The amniotic fluid transcriptome as a guide to understanding fetal disease.
Cold Spring Harbor Perspectives in Medicine, 2015 Numerous recent studies have shown the power of cell-free fetal RNA, obtained from amniotic fluid supernatant, to report on the development of the living fetus in real time.
Lillian M. Zwemer, D. Bianchi
semanticscholar +1 more source
Molecular Oncology, EarlyView.Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo +11 more
wiley +1 more source
Cell Death and DiseaseCD24 is overexpressed in various tumours and considered a regulator of cell migration, invasion, and proliferation. Recent studies have found that CD24 on ovarian cancer (OC) and triple-negative breast cancer cells interacts with the inhibitory receptor ...
Jie Liu, Changsheng Yan, Shaohua Xu
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SOME MORPHOLOGICAL AND BIOLOGICAL CHARACTERS OF THE SPIRILLA (VIBRIO FETUS, N. SP.) ASSOCIATED WITH DISEASE OF THE FETAL MEMBRANES IN CATTLE [PDF]
, 1919 Theobald Smith, Marian S. Taylor
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