Results 151 to 160 of about 69,185 (238)

Reproductive Decision‐Making Among BRCA1/2 Pathogenic Variants Carriers and Physicians: Attitudes Toward Preimplantation and Prenatal Genetic Testing

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective The objective of this paper is to investigate the knowledge and attitudes of BRCA1/2 pathogenic variant carriers and gynecologists regarding preimplantation genetic tests for monogenic diseases (PGT‐M) and prenatal diagnosis (PND).
Marta D'Alonzo, Silvia Actis, Giulia Lavalle, Simona Suraci, Luca Pace, Valentina Elisabetta Bounous, Annamaria Ferrero   +6 more
wiley   +1 more source

Preferences of Pregnant Women and Healthcare Professionals on First‐Trimester Ultrasound Screening for Fetal Anomalies: A Discrete Choice Experiment

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective The first‐trimester anomaly scan (FTAS) allows early detection of fetal structural anomalies. Decisions on timing and scan protocol influence its performance. Understanding how pregnant women and healthcare professionals value these aspects is essential for shaping screening programs.
Eline E. R. Lust, Kim Bronsgeest, Ian Smith, Lidewij Henneman, Neeltje M. T. H. Crombag, Caterina M. Bilardo, Robert‐Jan H. Galjaard, Esther Sikkel, Mireille N. Bekker, Monique C. Haak   +9 more
wiley   +1 more source

Glucocorticoid‐Induced TNFR‐Related Ligand as a Biomarker for Diagnosis and Severity of Asthma in Children

Pediatric Discovery, EarlyView.
Our study demonstrates elevated GITRL expression in HDM‐exposed dendritic cells (in vitro), murine asthma models, and pediatric asthma patients, and reveals a direct association between GITRL levels and disease severity in children. ABSTRACT Currently, there are no reliable pediatric biomarkers for assessing the severity of asthma. Therefore, the study
Yuehan Li, Yan Li, Jinying Xiang, Yinying Ren, Mi Zhou, Fang Deng, Zhou Fu, Fengxia Ding   +7 more
wiley   +1 more source

Dose Sildenafil Citrate Reduce the Incidence of Emergency Cesarean Section and Fetal Distress During Labor? A Randomized Double-Blinded Clinical Trial. [PDF]

J Reprod Infertil
Sharami SH, Milani F, Kabodmehri R, Naghdipour M, Mahmoudi Isaabadi A, Haghparast Ghadim-Limudahi Z.   +5 more
europepmc   +1 more source

Doppler Ultrasound Imaging Combined with Fetal Heart Detection in Predicting Fetal Distress in Pregnancy-Induced Hypertension under the Guidance of Artificial Intelligence Algorithm.

J Healthc Eng, 2021
Liu S, Sun Y, Luo N.
europepmc   +1 more source

Refractory Lung Diseases: From Cellular Structures, Molecular Mechanisms to Therapeutic Strategies

Pediatric Discovery, EarlyView.
ABSTRACT Refractory lung diseases (RLDs) encompass a spectrum of progressive pulmonary disorders, including acute respiratory distress syndrome (ARDS), bronchopulmonary dysplasia (BPD), and idiopathic pulmonary fibrosis (IPF). These conditions are defined by poor responsiveness to current therapeutic interventions and pose substantial clinical ...
Yiheng Qiu, Xiangyu Dong, Yi Zhu, Nicole Miranda, Awele Chukwura, Yan Peng, Sarina Zhao, Michelle Xiang, Peyton McGuire, Ava Zou, Lucas Zhang, Jiaming Fan, Linghuan Zhang   +12 more
wiley   +1 more source

Genetic correlations and clinical value of increased renal echogenicity in fetuses identified by prenatal ultrasonography

Precision Medical Sciences, EarlyView.
The corresponding images are as follows: enhanced fetal renal echo, enhanced fetal renal echo complicated with hydronephrosis, cardiac abnormality, chromosome microarray analysis: microdeletion of chromosome 17, whole‐exome sequencing: microdeletion of chromosome 17.
Haihong Liu, Yun Wu, Li Cao, Ting Zhou, LiJun Wu   +4 more
wiley   +1 more source

Epigallocatechin‐3‐Gallate Suppresses Glioma by Targeting Integrin αvβ3/FAK/ERK Signaling Axis and Matrix Metalloproteinases

Phytotherapy Research, EarlyView.
EGCG suppresses glioma progression by targeting integrin αvβ3/FAK/ERK signaling and inhibiting MMP‐2/MMP‐9‐mediated ECM degradation, thereby blocking proliferation, migration, invasion, and promoting apoptosis. ABSTRACT Epigallocatechin‐3‐gallate (EGCG), the most abundant and biologically active catechin in green tea, has been widely reported to ...
Rui Sun, Yonghan Pan, Ning Yang, Bing Kang, Hong Xiao, Xianglong Tang, Taiping Li, Mengjie Zhao   +7 more
wiley   +1 more source

Oral misoprostol (PGE1) vs vaginal dinoprostone (PGE2) for labor induction: individual participant data meta‐analysis of randomized controlled trials

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of oral misoprostol vs vaginal dinoprostone for the induction of labor (IOL) using an individual participant data (IPD) meta‐analysis. Methods We used a Cochrane review and searched Ovid MEDLINE, Ovid Embase, Ovid Emcare, CINAHL Plus, Scopus and ClinicalTrials.gov to identify randomized ...
S. Y. Tan, N. Au, M. D. Peel, J. M. Dodd, A. Deussen, P. A. Le Roux, D. C. Young, F. Tessier, P. Dallenbäch, D. M. R. Croll, M. Patabendige, K. Palmer, W. Li, B. W. Mol   +13 more
wiley   +1 more source

Angiogenic factors and fetal Doppler for predicting adverse pregnancy outcome in early‐onset small fetuses with and without pre‐eclampsia

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objectives To assess the predictive performance of angiogenic factors and fetal Doppler, alone and in combination, for composite adverse perinatal outcome (CAPO) in early‐onset small‐for‐gestational age (SGA) and fetal growth restriction (FGR), in cases both with and without pre‐eclampsia (PE), in order to evaluate the ability of these markers
E. Bonacina, M. Armengol‐Alsina, A. Casellas, M. Dalmau, P. Diaz, E. Roldán, J. Temprado, M. Duaso, Q. Ampurdanes, M. San José, T. Armengol, Z. Lizarraga, N. Maiz, M. Mendoza   +13 more
wiley   +1 more source