Results 151 to 160 of about 72,689 (257)

Pregnancy outcome following minor trauma during third trimester of pregnancy in Primiparous women: A propensity score–matched cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To determine the impact of minor trauma during pregnancy on adverse pregnancy outcome in primiparous women. Methods A retrospective cohort study was conducted at a single, tertiary university‐affiliated medical center between 2012 and 2023. Primiparous women aged 18 to 45 years who experienced minor trauma (Injury Severity Score ≤ 9)
Maayan Maor   +5 more
wiley   +1 more source

Strategies and mechanisms of precision genome engineering: From gene editing to genome writing

open access: yesiMetaOmics, EarlyView.
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang   +19 more
wiley   +1 more source

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

open access: yesiMetaOmics, EarlyView.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang   +16 more
wiley   +1 more source

Maternal and infant gut microbiome

open access: yesiMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang   +25 more
wiley   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Dose Sildenafil Citrate Reduce the Incidence of Emergency Cesarean Section and Fetal Distress During Labor? A Randomized Double-Blinded Clinical Trial. [PDF]

open access: yesJ Reprod Infertil
Sharami SH   +5 more
europepmc   +1 more source

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