Results 201 to 210 of about 487,341 (298)

Physical activity during pregnancy in women with type 1 or type 2 diabetes: A scoping review

Diabetic Medicine, EarlyView.
Abstract Aim Physical activity (PA) is recommended during pregnancy for its health benefits. While general PA guidance exists for uncomplicated pregnancies, evidence specific to women with pre‐existing type 1 diabetes or type 2 diabetes (T1D; T2D) is limited.
Holly Mei Jones, Lolwa Alyafei, Laura Macro, Gina Gardener, Emma Cockcroft, Rob Andrews, Richard M. Pulsford   +6 more
wiley   +1 more source

Recombinant ADAMTS13 Ameliorates Liver Injury and Improves Hepatic Microcirculation in a Murine Acute‐on‐Chronic Liver Failure Model

Hepatology Research, EarlyView.
ABSTRACT Aim The therapeutic significance of recombinant a disintegrin‐like and metalloprotease with thrombospondin type 1 motif 13 (rADAMTS13) in acute‐on‐chronic liver failure (ACLF) remains unclear. We aimed to investigate the therapeutic effects of rADAMTS13 in a murine model of ACLF‐like liver injury.
Jun‐ichi Hanatani, Norihisa Nishimura, Kosuke Kaji, Masayoshi Takami, Hiroyuki Masuda, Hiroaki Takaya, Koh Kitagawa, Shinya Sato, Tadashi Namisaki, Hitoshi Yoshiji   +9 more
wiley   +1 more source

WTAP‐mediated m6A RNA methylation promotes diabetic foot ulcer healing under negative pressure wound therapy

Journal of Diabetes Investigation, EarlyView.
NPWT significantly increases the suppressed WTAP and m6A levels in DFU patients, correlating directly with better 4‐week healing outcomes. In vitro, negative pressure reverses high‐glucose‐induced WTAP downregulation, restoring the cell proliferation and migration necessary for wound repair.
Yutong Li, Wenhua Chen, Jianhao Lu, Xiaoyue Lin, Ying Tang, Jiaxu Li, Mingwei Chen   +6 more
wiley   +1 more source

Comparison of three gestational weight gain guidelines for adverse pregnancy outcomes in Chinese women with gestational diabetes: A cohort study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background This study aimed to assess the associations between post‐diagnostic gestational weight gain (GWG) and adverse pregnancy outcomes among women with gestational diabetes mellitus (GDM) and to systematically compare the predictive performance of three mainstream GWG guidelines (IOM‐2009, CNS‐2021, NHCC‐2023), so as to provide real‐world
Shuang Zhang, Weiqin Li, Nan Li, Jia Guo, Linglin Tan, Huikun Liu   +5 more
wiley   +1 more source

Intermittent Auscultation for Intrapartum Fetal Heart Rate Surveillance

Journal of Midwifery &Women's Health, EarlyView.
Abstract Fetal heart rate surveillance is a standard component of intrapartum care. The fetal heart rate can be evaluated using intermittent auscultation or electronic fetal monitoring. Research that has compared these 2 strategies found them to be equivalent with respect to long‐term neonatal outcomes.
Kristen Ostrem‐Niemcewicz, Jessica Holm, Lisa Kane Low   +2 more
wiley   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Mapping obstetric biobanks: A scoping review highlighting gaps in the study of alloimmunized pregnancies

Transfusion, EarlyView.
Abstract Background Maternal red cell alloimmunization can cause hemolytic disease of the fetus and newborn (HDFN), yet prediction of disease severity remains limited. Biobanks that link pregnancy biospecimens with clinical and laboratory data could accelerate translational research; however, the landscape of relevant obstetric biobanks has not been ...
Orlin Chowdhury, Chantal Armali, Catherine Devion, Sasha Kyser‐Burke, Akash Gupta, Noor Niyar N. Ladhani, Harley Meirovich, Hubert Tsui, Noah Zweig, Yulia Lin, Heather VanderMeulen   +10 more
wiley   +1 more source

Mechanical pressure on endothelial cells mediates remote ischaemic preconditioning‐induced neuroprotection via miR‐126

Experimental Physiology, EarlyView.
Abstract Remote ischaemic preconditioning (RIPC) uses brief limb ischaemia to protect distant organs, but the mechanism of travel of the protective signal remains unclear. This study investigated whether endothelial cells (ECs) contribute to RIPC‐induced neuroprotection and the underlying mechanisms.
Xiaojie Wang, Lei Yan, Hongwei Zhu, Yifan Li, Qi Liu, Wei Li, Kerui Gong, Zhijun Zhao, Chunyang Zhang, Gang Fu, Guo Shao, Xunming Ji   +11 more
wiley   +1 more source

The risk of late-onset fetal growth restriction and unfavorable neonatal outcomes among fetuses within the 10th-25th weight percentile: a prospective cohort study. [PDF]

Matern Health Neonatol Perinatol
Motevasselian M, Ranjbar A, Kashanian M, Eshraghi N, Hashemi N, Bojnordi TE, Salari M, Khalighi F, Esmaeili N.   +8 more
europepmc   +1 more source

Clearance of p16‐positive cardiac cells improves age‐related cardiac remodeling in mice

Experimental Physiology, EarlyView.
Abstract Senescent cells are characterized by expression of markers like p16 and secretion of profibrotic and proinflammatory factors. The role of cellular senescence in age‐related cardiac remodeling and dysfunction is incompletely understood. This study aimed to: (i) evaluate the effect of p16‐ positive cell clearance on cardiac function and ...
Mozhdeh Mehdizadeh, Martin Mackasey, Kimia Gharagozloo, Martin Aguilar, Patrice Naud, Allan Ochs, Nhung Vuong‐Robillard, Eric Thorin, Gerardo Ferbeyre, Jean‐Claude Tardif, Martin G. Sirois, Jean Francois Tanguay, Stanley Nattel   +12 more
wiley   +1 more source