Results 41 to 50 of about 487,341 (298)

Doppler sonography of the uterine and the cubital arteries in normal pregnancies, preeclampsia and intrauterine growth restriction: evidence for a systemic vessel involvement [PDF]

, 2006
Aims: The decrease in uterine resistance during normal pregnancy is known to be related to invading trophoblast cells which derive from placental tissue. Uterine and peripheral resistance is elevated in preeclampsia.
Oberhoffer, Renate, Kainer, Franz, Jundt, Katharina, Schiessl, Barbara, Friese, Klaus, Schiessl, B;Kainer, F;Oberhoffer, R;Jundt, K;Friese, K   +5 more
core   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Sex differences in umbilical artery Doppler indices: a longitudinal study

Biology of Sex Differences, 2018
Background Sexual dimorphism in placental size and function has been described. Whether this influences the clinically important umbilical artery (UA) waveform remains controversial, although a few cross-sectional studies have shown sex differences in UA
Christian Widnes, Kari Flo, Tom Wilsgaard, Torvid Kiserud, Ganesh Acharya   +4 more
doaj   +1 more source

A review of congenital heart block [PDF]

, 2003
Congenital heart block is a rare disorder. It has an incidence of about 1 in 22,000 live births. It may be associated with high mortality and morbidity.
Glickstein, J., Buyon, Jill P., Friedman, Deborah M., Duncanson, L.J.   +3 more
core  

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

A non-invasive multimodal foetal ECG–Doppler dataset for antenatal cardiology research

Scientific Data, 2021
Measurement(s) electrocardiogram (maternal) • abdominal electrocardiogram (fetal) • Respiratory Rate • pulsed-wave Doppler (fetal heart) • heart function measurement • heart electrical impulse conduction trait Technology Type(s) electrocardiography ...
Eleonora Sulas, Monica Urru, Roberto Tumbarello, Luigi Raffo, Reza Sameni, Danilo Pani   +5 more
doaj   +1 more source

Mechanical Fetal Simulator for Fetal Doppler Testing

Journal of Electronics, Electromedical Engineering, and Medical Informatics, 2022
The continuous use of fetal Doppler allows for discrepancies in values ​​that lead to misdiagnoses in patients. This study aims to determine the effect of sound source distance on the fetal simulator with the measurement point. The contribution of this research is that the mechanical fetal heart system has 4 distances so that later it can be analyzed ...
Arum Triwerdani, Syaifudin Syaifudin, Bedjo Utomo, Abdul Basit   +3 more
openaire   +1 more source

The Value of Fetal Cerebro-umbilical Doppler Indices in Predicting Umbilical Blood Gas Abnormalities and Apgar Score in Diabetic Pregnant Women

, 2023
Aim:There is conflicting data regarding the utility of Doppler indices in patients with diabetes. Our objective was to investigate the value of fetal Doppler parameters on umbilical blood gas abnormalities and Apgar scores in term diabetic pregnancies ...
Mehmet Serdar Kutuk, Mehmet Dolanbay, Taha Takmaz, Caglar Cetin   +3 more
core   +1 more source

High‐Density Type I Collagen Promotes IFN‐γ+ CD8+ T Cell Exhaustion via SAT1‐ASS1‐Mediated Glutamine Accumulation and Ferroptosis in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang, Shuangyue Pan, Lu Bai, Bin Li, Tiantian Liu, Jianing Cao, Mengdi Yang, Heda Zhang, Duancheng Guo, Wenxiang Zhi, Zhonghua Tao, Xichun Hu   +11 more
wiley   +1 more source