Results 121 to 130 of about 423,516 (231)

Clearance of p16‐positive cardiac cells improves age‐related cardiac remodeling in mice

Experimental Physiology, EarlyView.
Abstract Senescent cells are characterized by expression of markers like p16 and secretion of profibrotic and proinflammatory factors. The role of cellular senescence in age‐related cardiac remodeling and dysfunction is incompletely understood. This study aimed to: (i) evaluate the effect of p16‐ positive cell clearance on cardiac function and ...
Mozhdeh Mehdizadeh, Martin Mackasey, Kimia Gharagozloo, Martin Aguilar, Patrice Naud, Allan Ochs, Nhung Vuong‐Robillard, Eric Thorin, Gerardo Ferbeyre, Jean‐Claude Tardif, Martin G. Sirois, Jean Francois Tanguay, Stanley Nattel   +12 more
wiley   +1 more source

Clinical applications of fetal echocardiography

Archives of Acoustics, 2015
Recent advances of echocardiography have made it possible to study cardiac anatomy and circulatory physiology of fetus. We studied the foetal cardiac structures and physiology by cross-sectional and M-mode echocardiography in 200 fetuses at 32-40 weeks ...
Hideyo SHIMADA, Michiko TAKAHASJI, Shizuo KATAGIRI, Hideo KOBAYASHI, Kazuru SAITO   +4 more
doaj  

Successful Live Saving Management Critical CHD By Early Diagnosed Fetal Echocardiography [PDF]

Fetal echocardiography is a vital tool for identifying and assessing congenital heart disease (CHD), which accounts for 1% of live births globally. It offers significant prenatal and postnatal care benefits, potentially saving lives in severe cases ...
Indah Musdalifah Chaeruddin, Mahrus Abdur Rahman, I Ketut Alit Utamayasa, Taufiq Hidayat
core   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Referral Indications for Fetal Echocardiography at Dr. Shariati Hospital, Bandar Abbas: A Cross-Sectional Study [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Congenital heart defects (CHD) are among the most common congenital structural anomalies and a leading cause of neonatal mortality.
Khadijeh Riazi Kermani, Omid Mofidi, Shahrokh Rajaei   +2 more
doaj  

Role of reactive oxygen species in mediating peripheral hypoxic vasodilation and sympathoexcitation at high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude acclimatisation increases muscle sympathetic nerve activity (MSNA) via activation of the arterial chemoreflex, pulmonary arterial baroreceptors and resetting of the sympathetic vascular baroreflex. However attempting to silence these mechanisms only partially normalises MSNA, implicating other contributory ...
Liam D. Corr, Andrew J. M. Douglas, Elliott J. Jenkins, Lauren E. Maier, Jodie L. Koep, Travis D. Gibbons, Adam Field, James D. Anholm, Katharine Foster, Zoe H. Adams, Lydia L. Simpson, Jonathan P. Moore, Tinna Traustadottir, Christoph Siebenmann, Joshua C. Tremblay, Mike Stembridge   +15 more
wiley   +1 more source

Prenatal diagnosis and postnatal management of a complicated pulmonary valve stenosis: a case report

BMC Pediatrics
Background Pulmonary stenosis (PS) is a common congenital heart defect, often detectable prenatally via fetal echocardiography. This case report describes a fetus diagnosed at 19 weeks with severe valvular PS.
Alireza Golbabaei, Hooman Mohammad Talebi   +1 more
doaj   +1 more source

Prevalence and clinical significance of fetal tricuspid regurgitation during the third trimester of pregnancy

Revista Brasileira de Saúde Materno Infantil
Objectives: the aim of this study was to determine the prevalence of fetal tricuspid valve regurgitation (TR) during the third trimester of low-risk pregnancies and to assess its clinical significance on neonates.
Karina Reis de Melo Lopes, Emanuela Virginia Vale Cavalcante, Narjara Tiane Lopes de Melo, Susi Araújo Alves, João Guilherme Bezerra Alves, Alex Sandro Rolland Souza   +5 more
doaj   +2 more sources

Suspected Pentalogy of Cantrell With Ectopia Cordis in a Newborn: Diagnostic and Management Challenges in a Low Resource Setting in Northern Tanzania

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Suspected Pentalogy of Cantrell with ectopia cordis carries very high neonatal mortality. In low‐resource settings, absent antenatal ultrasound and limited access to imaging and pediatric cardiac surgery reduce diagnostic certainty and survival.
Tabitha Mshanga, Lightness Chuwa, Kajal Jethwa, Ronald Mbwasi   +3 more
wiley   +1 more source