Amentoflavone, a preferentially TGF‐ββ receptor 1 inhibitor, attenuates transverse aortic constriction (TAC)‐triggered cardiac hypertrophy, fibrosis, and dysfunction by suppressing downstream Smad and MAPK signaling cascades in cardiomyocytes and cardiac fibroblasts.
Jiangjiao Wu +10 more
wiley +1 more source
Clinical utility of fetal echocardiography: an Egyptian center experience. [PDF]
Al-Fahham MM +3 more
europepmc +1 more source
Hederagenin Attenuates Cardiac Remodeling by Targeting Phosphodiesterase 9A
ABSTRACT Background and Aim New therapeutic strategies for heart failure are urgently needed. The protective effects of cyclic guanosine monophosphate (cGMP)—protein kinase G (PKG) pathway on heart have been widely reported. Despite phosphodiesterase 9A (PDE9A) inhibitors combating cardiac remodeling, clinically available drugs are lacking. Hederagenin
Liqian Chen +16 more
wiley +1 more source
Betulin Protects Against Cardiac Hypertrophy by Improving AMPK/Nrf2‐Dependent Mitochondrial Function
Betulin effectively mitigates pressure overload‐induced cardiac hypertrophy in both Ang II‐infused and TAC‐operated mice. Mechanistically, betulin activated AMPK phosphorylation, promoted Nrf2 nuclear translocation, and upregulated antioxidant genes (HO‐1 and NQO‐1), thereby restoring mitochondrial function in cardiomyocytes.
Bei Zheng +8 more
wiley +1 more source
Accuracy of fetal echocardiography diagnosis and anticipated perinatal and early postnatal care in congenital heart disease in mid-gestation. [PDF]
Nurmi MO +3 more
europepmc +1 more source
We report a case of CO2 embolism complicated by severe ARDS with refractory hypoxia requiring extracorporeal membrane oxygenation (ECMO) therapy, which resulted in a favourable outcome. ABSTRACT Laparoscopic surgeries have revolutionised surgical practice due to their advantages, including minimal invasiveness, fewer postoperative complications ...
Jawdat Alali +5 more
wiley +1 more source
Novel and flexible ultrasound simulation with smartphones and tablets in fetal echocardiography. [PDF]
Hartmann TJ +8 more
europepmc +1 more source
Longitudinal maternal hemodynamics in high‐risk pregnancies with different subtypes of pre‐eclampsia
ABSTRACT Objective To evaluate maternal cardiac adaptation during pregnancy by comparing longitudinal hemodynamic profiles between women identified as high risk for preterm pre‐eclampsia (PE) who subsequently developed preterm PE, term PE or remained unaffected, as well as low‐risk women.
J. Lin +10 more
wiley +1 more source
Fetal echocardiography: A nine-year experience at a single tertiary center. [PDF]
Tosun O.
europepmc +1 more source
Factors causing timely referral for fetal echocardiography in the final diagnosis of congenital heart malformations: A cross-sectional study. [PDF]
Barati M +4 more
europepmc +1 more source

