Results 171 to 180 of about 1,194,310 (307)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Artificially induced torpor during pregnancy impairs fetal growth in mice. [PDF]

Sci Rep
Hagihara M, Sakurai T, Miyamichi K, Inada K.   +3 more
europepmc   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

Correction: Application of artificial intelligence in diagnosis and management of fetal growth disorders: a comprehensive review

Frontiers in Medicine
Frontiers Production Office
doaj   +1 more source

Neonatal brain MRI to prognosticate neurodevelopmental outcomes in fetal growth restricted infants: a systematic review. [PDF]

Front Pediatr
Ramdial R, MacNamara MA, Moldrich R, Colditz PB, Wixey JA.   +4 more
europepmc   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Fetal growth and congenital heart disease at high altitude. [PDF]

Philos Trans R Soc Lond B Biol Sci
Giussani DA.
europepmc   +1 more source

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

Advanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato, Haishuo Guan, Bianca M. Carrara, Mira Jacobs, Matteo Monticelli, Lukas Moser, Thomas Moragues, Andrew J. deMello, Tomaso Zambelli, Martin Ehrbar   +9 more
wiley   +1 more source

Psychological Experiences of Pregnant Women with Fetal Growth Restriction in China: A Qualitative Study. [PDF]

Int J Womens Health
Lin X, Chen T, Xu Y, Mei Y, Cai L, Zhou W.   +5 more
europepmc   +1 more source

Fetal Growth in Diabetic Pregnancies [PDF]

, 2012
Allcock, Kirsty, Anblagan, Devasuda, Bugg, George, Costigan, Carolyn, Deshpande, Ruta, Gowland, Penny A, Jones, Nia, Leach, Lopa, Mansell, Peter, Pitiot, Alain, Raine-Fenning, Nick   +10 more
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