Results 111 to 120 of about 266,924 (341)

Association between fetal growth restriction and polymorphisms at sites -1 and +3 of pituitary growth hormone: a case-control study

BMC Pregnancy and Childbirth, 2005
Background Fetal growth restriction is associated with significantly increased risks of neonatal death and morbidity and with susceptibility to hypertension, cardiovascular disease and NIDDM later in life.
Vaidya Rehana, Campese Caroline, Adkins Ronald M, Boyd Theonia K   +3 more
doaj   +1 more source

Undernutrition and stage of gestation influence fetal adipose tissue gene expression [PDF]

, 2015
Funded by the Scottish Government’s Rural and Environment Science and Analytical Services Division (RESAS), including the Strategic Partnership for Animal Science Excellence (SPASE) and the U.S. National Institutes of Health (HD045784).
Adam, Clare L, Aitken, Raymond P, Horgan, Graham W, Luther, Justin S, Milne, John S, Redmer, Dale A, Reynolds, Lawrence P., Wallace, Jacqueline M   +7 more
core   +1 more source

Fetal Growth Restriction

, 2015
The studies reported in this thesis provide insight into the course of fetal growth restriction (FGR) from the prenatal period until school age. In part I we report on fetal cardiac function and found that left, right, and septal longitudinal annular displacement is reduced in FGR compared to age-matched controls when measured with an offline four ...
  +5 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Plasma metabolites are altered before and after diagnosis of preeclampsia or fetal growth restriction

Scientific Reports
Metabolomics is the study of small molecules (metabolites), within cells, tissues and biofluids. Maternal metabolites can provide important insight into the health and development of both mother and fetus throughout pregnancy.
Lucy A. Bartho, Daniel R. McKeating, Susan P. Walker, Brunda Nijagal, Teresa M. MacDonald, Natasha Pritchard, Natalie J. Hannan, Anthony V. Perkins, Stephen Tong, Tu’uhevaha J. Kaitu’u-Lino   +9 more
doaj   +1 more source

A possible new approach in the prediction of late gestational hypertension: The role of the fetal aortic intima-media thickness [PDF]

, 2017
The aim was to determine the predictive role of combined screening for late-onset gestational hypertension by fetal ultrasound measurements, third trimester uterine arteries (UtAs) Doppler imaging, and maternal history.
Camerin, Martina, Cosmi, Erich, Grisan, Enrico, Londero, Ambrogio P., Visentin, Silvia   +4 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Factors associated with ultrasound-aided detection of suboptimal fetal growth in a malaria-endemic area in Papua New Guinea [PDF]

, 2015
BACKGROUND: Fetal growth restriction (FGR) is associated with increased infant mortality rates and ill-health in adulthood. Evaluation of fetal growth requires ultrasound.
Karl, Stephan, Mueller, Ivo, Ome-Kaius, Maria, Rogerson, Stephen John, Siba, Peter, Singirok, Dupain, Unger, Holger Werner, Walker, Jane, Wangnapi, Regina A.   +8 more
core   +1 more source

Hemodynamic factors associated with fetal cardiac remodeling in late fetal growth restriction: a prospective study [PDF]

, 2019
Giuseppe Rizzo, C. Mattioli, Ilenia Mappa, В. О. Бицадзе, J. Kh. Khizroeva, Maciej Słodki, A. Makatsarya, F. D’Antonio   +7 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source