Results 121 to 130 of about 266,924 (341)

Fetal Growth Restriction - a 4-Year Case Series [PDF]

, 2013
Overview and aims: Fetal growth restriction (FGR) affects 15% of pregnancies and is associated with both increased perinatal and neonatal morbidity and mortality and long-term effects in adult life. Our aim was to describe cases and outcomes of FGR from
Figueiredo, A, Martins, AT, Martins, I, Pedroso, C, Ribeiro, F, Robalo, R   +5 more
core  

Cell free hemoglobin in the fetoplacental circulation: a novel cause of fetal growth restriction? [PDF]

, 2018
Adam Brook, Annie Hoaksey, Rekha Gurung, Edward E. C. Yoong, Rosanna Sneyd, Georgia Baynes, Helen Bischof, Sarah Jones, Lucy Higgins, Carolyn Jones, Susan Greenwood, R.C. Jones, Magnus Gram, Ingrid Lang, Gernot Desoyé, Jenny Myers, Henning Schneider, Stefan R. Hansson, Ian Crocker, Paul Brownbill   +19 more
openalex   +1 more source

Femur development in fetal growth restriction as observed on prenatal magnetic resonance imaging [PDF]

, 2022
Stefan F. Nemec, Ursula Nemec, Daniela Prayer, Michael Weber, Dieter Bettelheim, Gregor Kasprian   +5 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Male fetal sex affects uteroplacental angiogenesis in growth restriction mouse model†

, 2021
Jessica F. Hebert, Jess A. Millar, Rahul Raghavan, Amie Romney, Jason E. Podrabsky, Monique Y. Rennie, Allison M. Felker, Perrie O’Tierney-Ginn, Mayu Morita, Elizabeth DuPriest, Terry K. Morgan   +10 more
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

OC02.05: Ductus venosus velocity ratios for prediction of neonatal cardiac dysfunction in early severe fetal growth restriction [PDF]

, 2016
N. Fratelli, R. Magri, Cristina Zanardini, A. Fichera, V. Azzaretto, A. Vitucci, C. Cavalli, Rossana Orabona, A. Valcamonico, Federico Prefumo   +9 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source