Results 141 to 150 of about 5,584,012 (303)

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Curva dos valores normais de peso fetal estimado por ultra-sonografia segundo a idade gestacional

open access: yesCadernos de Saúde Pública
Este trabalho teve por objetivo avaliar a evolução do peso fetal estimado em gestações normais de 20 a 42 semanas. Quanto ao desenho e métodos empregados na pesquisa, realizou-se estudo descritivo de um universo constituído por 2.874 gestantes normais da
José Guilherme Cecatti   +3 more
doaj  

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

The role of angiogenic growth factors in placental dysfunction and fetal growth retardation

open access: yes, 2014
Результати проведених досліджень свідчать, що визначення показників рівня факторів росту в комплексі з фетометрією, допплерівськими дослідженнями кровотоку, кардіотокографією дозволяє прогнозувати розвиток й оцінювати ступінь тяжкості синдрому ЗРП.
Артьоменко, В. В.   +1 more
core  

Case Report Sildenafil Citrate in Fetal Growth Restriction

open access: yes, 2020
Background: Pregnancies with early onset fetal growth restriction have poor perinatal outcome. Sildenafil citrate (PDE -5 inhibitor) as a vasodilator increases uteroplacental blood flow and potentiates fetal growth.
Hossain Md Nowroz   +2 more
core  

A etiopatogênese do processo de Restrição de Crescimento Intra-Uterino: um estudo bibliográfico

open access: yesRevista Eletrônica de Enfermagem, 2008
Revisão bibliográfica, realizada junto aos bancos de dados MEDLINE, SciELO, ScienceDirect e LILACS, com o objetivo de identificar a produção científica na área de saúde sobre os principais fatores envolvidos na etiopatogênese do processo de Restrição de
Ana Karina Marques Salge   +11 more
doaj  

Doppler and fetal growth retardation. [PDF]

open access: yesArchives of Disease in Childhood, 1993
R B, Beattie, M J, Whittle
openaire   +2 more sources

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

open access: yesAdvanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu   +10 more
wiley   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

open access: yesAdvanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries   +25 more
wiley   +1 more source

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