Results 51 to 60 of about 101,214 (307)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Relationships between fetal body weight of Wistar rats at term and the extent of skeletal ossification

open access: yesBrazilian Journal of Medical and Biological Research, 2005
We investigated the relationship between fetal body weight at term (pregnancy day 21) and the extent of ossification of sternum, metacarpus, metatarsus, phalanges (proximal, medial and distal) of fore- and hindlimbs and cervical and coccygeal vertebrae ...
I. Chahoud, F.J.R. Paumgartten
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A Case Report of Silver-Russell Syndrome in Iran

open access: yesJournal of Dental School, 2020
Objectives Silver-Russell syndrome (SRS) is a rare genetic disorder which is typically characterized by prenatal and postnatal growth failure and asymmetry in the size of the two halves or other parts of the body.
Arezoo Mahdian   +2 more
doaj   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

THE ROLE OF GROWTH AND ENDOTHELIAL FACTORS IN HEMOSTATIC DISORDER IN CHILDREN WITH THE SYNDROM DELAYED FETAL

open access: yesМедицинский вестник Юга России, 2013
Violation of the natural defense mechanisms of endothelial dysfunction and an imbalance can occur many neurohumoral factors. The imbalance of angiogenic and antiangiogenic growth factors, endothelial, platelet factor closely related to disorders of ...
S. B. Berezhanskaya   +3 more
doaj   +1 more source

Impact of coronavirus disease (Covid-19) within the third trimester of pregnancy

open access: yesJournal of Education, Health and Sport, 2020
Introduction. Assessment of pregnancy, fetal status, diagnosis of placental insufficiency (PI) in pregnant women with coronavirus COVID-19, is a topical issue in obstetric practice and is of great social value for the birth of healthy children.The aim of
A. V. Boychuk   +2 more
doaj   +1 more source

Different Effects of Maternal Low-Isoflavone Soy Protein and Genistein Consumption on Hepatic Lipid Metabolism of 21-Day-Old Male Rat Offspring. [PDF]

open access: yes, 2017
Amino acid composition and isoflavone are alleged contributors to the beneficial effects of soy protein isolate (SPI) on lipid metabolism. Therefore, we investigated the contributing component(s) of SPI in a maternal diet to the regulation of lipid ...
Han, Anna, Kwon, Young Hye, Won, Sae Bom
core   +3 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Micronutrient Intake and Fundal Height Determine Birth Weight [PDF]

open access: yes, 2019
The birth weight (BW) are utilized as indicators of the healthy and term newborns. Factor that affects the weight of a newborn are micronutrient intake and fundal height. Folic acid and iron (Fe) were associated with newborn birth weight.
Aghadiati, F. (Faradina)   +2 more
core   +3 more sources

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