Results 71 to 80 of about 251,789 (347)
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Violation of the natural defense mechanisms of endothelial dysfunction and an imbalance can occur many neurohumoral factors. The imbalance of angiogenic and antiangiogenic growth factors, endothelial, platelet factor closely related to disorders of ...
S. B. Berezhanskaya +3 more
doaj +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Impact of coronavirus disease (Covid-19) within the third trimester of pregnancy
Introduction. Assessment of pregnancy, fetal status, diagnosis of placental insufficiency (PI) in pregnant women with coronavirus COVID-19, is a topical issue in obstetric practice and is of great social value for the birth of healthy children.The aim of
A. V. Boychuk +2 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
The physiological significance of insemination in programming pregnancy outcome [PDF]
The cellular and molecular environment of the uterus during the pre - and peri - implantation period of early pregnancy is critical for implantation success and optimal fetal and placental development.
Bromfield, John James
core +6 more sources
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
71 Experimental Fetal Growth Retardation [PDF]
Reduction of uteroplacental blood flow in one uterine horn of pregnant rats was achieved by Wigglesworth's technique (ligation of uterine vessels at lower end of one horn on the 17th day of pregnancy). Cesarian section was performed on the 21st day. Fetal death or stunting occurred in fetuses located near the ligation.
openaire +1 more source
Morbidity and Mortality ofVery Low Birth Weight Infant Graduates of a Level Three Neonatal Intensive Care Unit [PDF]
Purpose: To describe the morbidity and mortality of very low birth weight (VLBW) infant graduates of a level three neonatal intensive care unit (NICU) in a medically underserved population.
Cortes, Maria
core +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source

