Results 131 to 140 of about 7,676,209 (212)

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang   +8 more
wiley   +1 more source

MS

open access: yes, 2008
thesisThe purpose of this descriptive study was to determine the relationship between the fetal heart rate during the last trimester of pregnancy and the sex of the baby.
Nash, Teresa Burt
core  

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

MZF1 Inhibits TGFβ‐1/SMAD Signaling by Transcriptionally Activating SnoN to Augment Tumorigenic Potential in Colon Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies MZF1 as a core regulator of colon cancer via SnoN‐mediated TGF‐β suppression, proposes 10Panx Acetate as a targeted inhibitor, and validates MZF1/SnoN as prognostic markers for aggressive disease. ABSTRACT Colon cancer progression is associated with transcriptional and signaling abnormalities.
Siqi Sheng   +9 more
wiley   +1 more source

Significance of bradycardia during antenatal fetal heart rate monitoring

open access: yes, 1988
CITATION: Diergaardt, E. W. P. & Odendaal, H. J. 1988. Significance of bradycardia during antenatal fetal heart rate monitoring. South African Medical Journal, 73:173-174.The original publication is available at http://www.samj.org.zaAll antenatal fetal ...
Diergaardt, E. W. P., Odendaal, H. J.
core  

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

open access: yesAdvanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong   +11 more
wiley   +1 more source

The role of brief mindfulness meditation instruction and practice in changing biophysical indicators in pregnant women and their babies [PDF]

open access: yes, 2012
Pregnancy is a time of change that has the potential to be a stressful experience for some women. There is evidence from animal and human studies that longterm exposure to maternal stress can be detrimental to the unborn baby, both before and after birth.
Clark, Mary Rosanne
core  

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

open access: yesAdvanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian   +10 more
wiley   +1 more source

Fetal heart rate variability and monitoring in gestational diabetes mellitus: a narrative review

open access: yes
Objective To evaluate evidence on fetal heart rate variability (HRV) in pregnancies complicated by gestational diabetes mellitus (GDM), focusing on cardiotocography (CTG), computerized CTG (cCTG), fetal electrocardiography (ECG), and magnetocardio­graphy
Mariarosaria Motta   +27 more
core   +1 more source

Fetal Heart Rate estimation on non Invasive ECG

open access: yesTecnoLógicas, 2013
This paper describes a method for locating QRS complex in noninvasive FECG, using techniques based on MECG cancellation, and Principal Component Analysis.
Luis O. Sarmiento-Alvarez   +3 more
doaj  

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