Results 161 to 170 of about 346,756 (303)

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

Advanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner, Raith Nowak, Stephanie M. Kronstadt, Nicholas H. Pirolli, Talia J. Solomon, Kristin Nikolov, William Pieper Holeman, Ian M. Smith, Kimberly M. Stroka, John P. Fisher, Steven M. Jay   +10 more
wiley   +1 more source

Magnitude, associated factors, and immediate outcomes of nonreassuring fetal heart rate status among laboring mothers in Ethiopia: a systematic review and meta-analysis. [PDF]

AJOG Glob Rep
Yilak G, Molla B, Tilahun BD, Abate BB, Kitaw TA, Kassie A, Getie A, Erega BB, Ayele M, Lake ES.   +9 more
europepmc   +1 more source

High‐Throughput 3D Matrigel‐based Droplet Microfluidics for Single‐Cell Function‐to‐Omics Analysis of Cytotoxic Immune Cells in Solid Tumor Interactions

Advanced Materials Technologies, EarlyView.
A 3D Matrigel‐based droplet microfluidics platform that allows physiologically relevant analysis of single immune‐tumor interactions in solid tumors. By integrating real‐time functional imaging with fluorescence‐activated droplet sorting and RNA sequencing, the system links immune cytotoxic behavior to transcriptomic profiles, providing a scalable ...
Christina Sharkey, Harry Akligoh, Michael Finocchiaro, Abhishek Srihari Rampelli, Zongwei Wang, Aria F. Olumi, Tania Konry   +6 more
wiley   +1 more source

Intrapartum Fetal Heart Rate Pattern Evolution Associated With Septuple Nuchal Cord Loops: A Case Report. [PDF]

Case Rep Obstet Gynecol
Sugimoto M, Nakao M, Nii M, Sakakibara K, Kotaka S, Nimura R, Senda T, Maeda Y, Hirata T, Ikeda T.   +9 more
europepmc   +1 more source

Additive Manufacturing of Patient‐Specific Intracranial Aneurysm Cell Culture Models

Advanced Materials Technologies, EarlyView.
Patient‐specific intracranial aneurysm models were fabricated using chocolate moulding, 3D printed water‐soluble cores, and direct resin 3D printing. Moulding PDMS around sacrificial cores made of chocolate or 3D printed water‐soluble resin yielded accurate, expandable, and endothelializable models that outperformed resin‐based approaches.
Chloe M. de Nys, Jaimee‐Lee Wood, James I. Novak, Danilo Carluccio, Craig D. Winter, Ashley R. Murphy, Mark C. Allenby   +6 more
wiley   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Antepartum Computerized Cardiotocography in High-Risk Pregnancies: Comparative Analysis of Fetal Heart Rate Parameters in Hypertensive Disorders of Pregnancy, Diabetes and Intrahepatic Cholestasis. [PDF]

J Clin Med
Danciu BM, Simionescu AA.
europepmc   +1 more source

Wet Ball Milling Synthesis of Iron Oxide Nanoparticles for High‐Efficiency, Controllable Magnetic Hyperthermia in Ovarian Cancer

Advanced Materials Technologies, EarlyView.
A wet ball‐milling method is presented to synthesize iron magnetic nanoparticles and evaluate their magnetic hyperthermia performance. Optimized particles (∼270 nm, Ms ∼114 emu/g) achieve ∼50°C heating under clinically safe alternating magnetic fields, while pulsed‐field operation enables controlled temperature regulation (∼30°C).
Shahriar Mostufa, Bahareh Rezaei, Md Shahriar, Karla Mercedes Paz González, Anil Kumar, Changxue Xu, Yun Suk Eo, Ioannis H. Karampelas, Jenifer Gómez‐Pastora, Rui He, Kai Wu   +10 more
wiley   +1 more source

Development of a novel artificial intelligence algorithm for interpreting fetal heart rate and uterine activity data in cardiotocography. [PDF]

Front Digit Health
Pardasani R, Vitullo R, Harris S, Yapici HO, Beard J.   +4 more
europepmc   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source