Results 141 to 150 of about 53,221 (295)

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

Advanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang, Yizhong Liang, Manan Sulaiman, Jiaqi Du, Ming Jiang, Zhihua Wang, Xu Yu, Li Xu   +7 more
wiley   +1 more source

Fetal Heart Rate Self-Monitoring by Mothers in Labor

Childbirth poses a significant risk, with many intrapartum stillbirths worldwide. In Lesotho, 35% of stillbirths occur during labor, predominantly due to birth asphyxia.
Zbelo, Mesfin Gebrekidan
core  

Printable Conductive Hydrogels for Electrochemical Biosensing and Soft Bioelectronic Interfaces

Advanced Science, EarlyView.
Flexible, conductive hydrogels that integrate printability, mechanical tunability, biocompatibility, and electronic performance remain challenging to achieve. Here, we develop 3D‐printable poly(ethylene glycol)–poly(pyrrole)‐ hydrogels with tissue‐like mechanics, high cytocompatibility, and robust electrochemical function.
Lukas Hein, Renan Colucci, Xin Wei, Tsvetomir Ivanov, Katharina Landfester, Ulrike Kraft, Maria Villiou   +6 more
wiley   +1 more source

Frequent fetal heart-rate monitoring for early detection of abruptio placentae in severe proteinuric hypertension

, 1988
CITATION: Odendaal, H. J. et al. 1988. Frequent fetal heart-rate monitoring for early detection of abruptio placentae in severe proteinuric hypertension. South African Medical Journal, 74:19-21.The original publication is available at http://www.samj.org.
Grove, D., Pattinson, R. C., Odendaal, H. J., Du Toit, R.   +3 more
core  

Clinical application of continuous fetal heart rate monitoring in active stage

Huli yanjiu, 2005
[目的]观察活跃期持续胎心监护在早期发现胎儿窘迫及新生儿窒息方面的应用效果。[方法]观察组3025例产妇在活跃期应用持续胎心监护,对照组3108例产妇采用常规临产后行单次有刺激试验检查。[结果]观察组胎儿窘迫的诊断率为3.47%,显著高于对照组（1.71%）,新生儿窒息的发生率为4.79%,其中轻度窒息的发生率为4.50%,重度窒息的发生率为0.30%,显著低于对照组 ...
黄秋群, 黄雪群
doaj  

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

The role of brief mindfulness meditation instruction and practice in changing biophysical indicators in pregnant women and their babies

, 2012
Pregnancy is a time of change that has the potential to be a stressful experience for some women. There is evidence from animal and human studies that longterm exposure to maternal stress can be detrimental to the unborn baby, both before and after birth.
Clark, Mary Rosanne
core  

Midwives' and Women's Perception on Moyo Fetal Heart Rate Monitor for Intrapartum Fetal Heart Rate Monitoring; A Cross-Sectional Study. [PDF]

Med Devices (Auckl), 2020
Mdoe P, Yeconia A, Buu F, Kusulla S, Blacy L, Guga G, Mduma E, Kidanto H.   +7 more
europepmc   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source