Results 151 to 160 of about 1,339,121 (337)
The paper presents a current state of knowledge on the regulation of Hb synthesis in physiology and pathology. Possible mechanisms of HbF synthesis switching and an influence of different drugs on HbF production have been described.
openaire +1 more source
Fetal alcohol syndrome; guidelines for referral and diagnosis [PDF]
National Center on Birth Defects and Developmental Disabilities in coordination with National Task Force on Fetal Alcohol Syndrome and Fetal Alcohol Effect (American Academy of Pediatrics, American College of Obstetricians and Gynecologists, March of ...
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Effect of Ultraviolet Irradiation on Hemoglobin Oxidation [PDF]
The autoxidation of hemoglobin was markedly increased when the solution of hemoglobin was irradiated by ultraviolet (UV) ray under aerobic conditions. The oxidation of hemoglobin was not observed when hemoglobin was irradiated with UV ray under anaerobic
897, 富岡, 和久
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Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu +12 more
wiley +1 more source
Hereditary persistence of fetal hemoglobin is an uncommon, benign disorder in which the expression of gamma-globin genes persists into adult life. Several point mutations have been associated with the increased gamma-globin gene promoter activity.
Schreiber R. +5 more
doaj
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao +13 more
wiley +1 more source
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley +1 more source
BackgroundPregnant individuals with sickle cell disease (SCD) face high maternal and fetal complication rates. While some studies suggest transfusions may improve outcomes, evidence is limited.
Ram Prakash Thirugnanasambandam +1 more
doaj +1 more source
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao +10 more
wiley +1 more source
Rapid fetal hemoglobin estimation assay during cordocentesis
A method for rapid estimation of fetal blood content during cordocentesis is described. This procedure gives an opportunity to determine the contamination of the fetal sample by maternal blood as soon as possible.
Loizou, P. +4 more
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