Results 251 to 260 of about 72,054 (299)

Fetal Hemoglobin Variants in Mice

Science, 1968
Two strains of mice, DBA and C3H, have a fetal globin polypeptide chain which differs in electrophoretic mobility from the corresponding fetal chain of the C57B1 strain. Mice of the DBA and C3H strains also differ from those of the C57B1 in adult hemoglobin type. Results of backcrossing the (DBA × C57B1) hybrid to the C57B1 suggest that the fetal chain
Gilman, J G, Smithies, O
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Fetal hemoglobin levels in adults

Blood Reviews, 1994
The synthesis of fetal hemoglobin (HbF) is normally reduced to very low levels of less than 0.6% of the total hemoglobin in adults. The HbF is restricted to a sub-population of erythrocytes termed 'F-cells'; 85% of the normal adult population have 0.3% to 4.4% F-cells.
J. Rochette, J.E. Craig, S.L. Thein, J. Rochette   +3 more
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The Bohr effect of fetal hemoglobin

American Journal of Obstetrics and Gynecology, 1968
Abstract The Bohr effect of solutions of hemoglobin A, F, and A-F was studied. Between pH 7.2 and pH 7.8 the calculated Bohr effect was φ = −0.48 for all three solutions. However, between pH 7.2 and pH 6.5 the Bohr effect of hemoglobin F was greater (φ = −0.51) than hemoglobin A (φ = −0.43).
L I, Mann, S L, Romney
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The initiation of fetal hemoglobin biosynthesis

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1979
Biosynthesis of the alpha and beta chains of rabbit and human adult hemoglobin is initiated with a methionyl residue, which is removed during elongation of the peptide chain. To study the initiation of biosynthesis of the delta chain of human fetal hemoglobin, fresh placental blood was used for labeling experiments with radioactive amino acids. Labeled
H, Imanishi, H, Suzuki, H A, Itano
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The heterogeneity of the fetal hemoglobin of the goat

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1969
Abstract The heterogeneity of the goat fetal hemoglobin, which has been observed by measurements of the rate of denaturation in an alkaline medium, was reinvestigated. Analyses of the amino acid compositions of various peptides isolated from a tryptic digest of the γ chain failed to demonstrate a molecular heterogeneity.
J B, Wilson, H R, Adams, T H, Huisman
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The oxygen capacity of fetal hemoglobin

American Journal of Obstetrics and Gynecology, 1964
Abstract The oxygen capacity of fetal blood has been noted to be the same as that of the blood of the human adult. Statistical considerations allow the assumption that the oxygen capacity of fetal hemoglobin is the same as that of the adult hemoglobin as defined by resistance to alkaline denaturation.
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Fetal Hemoglobin Alters Hemoglobin A_1c Measurements

Annals of Internal Medicine, 1991
Excerpt To the editors:The letter of Holt and colleagues (1) emphasizes that diabetic subjects with hemoglobin S or C traits will have a falsely low hemoglobin A1cvalue if measured by certain metho...
R W, Bergstrom, J R, Kelley, W K, Ward
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Hemoglobin C in association with hereditary persistence of fetal hemoglobin

Postgraduate Medicine, 1987
Hemoglobin C and hereditary persistence of fetal hemoglobin (HPFH) are an uncommon combination of hemoglobinopathies. Several tests are needed to verify this condition, among them hemoglobin electrophoresis and Kleihauer-Betke staining of a peripheral blood smear.
A W, Martin, S B, Lippmann, M M, Keeling, J A, Lynch, M, Martinez   +4 more
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Fetal Hemoglobin in Neonatal Anemia

Pediatrics, 1991
To the Editor.— A recent paper in Pediatrics by Bard and Prosmanne1 described an elevation of fetal hemoglobin (Hb-F) production in infants with bronchopulmonary dysplasia (BPD) and oxygen dependency. The authors described a novel approach to the evaluation of occult hypoxemia in infants, with potential application in a wide range of ...
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Mouse hemoglobin during gestation Absence of fetal hemoglobin

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1982
A "fetal hemoglobin' has been reported to exist during mouse gestation, Investigations using CMC chromatography, starch gel electrophoresis or isoelectric focusing have shown a hemoglobin band from fetal tissues, and blood was obtained which was different from the adult hemoglobin and designated a "fetal hemoglobin'.
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