Results 241 to 250 of about 72,054 (299)
Elevating fetal hemoglobin: recently discovered regulators and mechanisms.
BloodKhandros E, Blobel GA, Blobel GA.
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PGC-1α agonism induces fetal hemoglobin and exerts antisickling effects in sickle cell disease. [PDF]
Sci AdvSun Y +13 more
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Oxygen Transport by Fetal Bovine Hemoglobin [PDF]
Journal of Molecular Biology, 1996 The functional properties of fetal bovine hemoglobin have been studied as a function of temperature, chloride and 2,3-diphosphoglycerate (DPG) concentration. The fetal bovine erythrocyte has six times the concentration of the allosteric modulator DPG compared with the adult cell, and yet the oxygen affinity of the fetal hemoglobin still exceeds that of
Clementi, Maria Elisabetta +5 more
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Biochimica et Biophysica Acta (BBA) - Protein Structure, 1978
Using isoelectric focusing, a fetal hemoglobin was found in the peripheral blood of C57BL/6 fetal mouse during the 14 to 20 days gestational period. In acid-urea polyacrylamide gel the pattern of this fetal hemoglobin was different from that of the adult hemoglobin.
Wu, N, Sikkema, D A, Zucker, R M
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Using isoelectric focusing, a fetal hemoglobin was found in the peripheral blood of C57BL/6 fetal mouse during the 14 to 20 days gestational period. In acid-urea polyacrylamide gel the pattern of this fetal hemoglobin was different from that of the adult hemoglobin.
Wu, N, Sikkema, D A, Zucker, R M
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2023
Abstract Fetal hemoglobin (HbF) is a physiologic variant of the adult hemoglobin (HbA) protein. It is primarily present in the fetus. HbA has a lower oxygen affinity than HbF. A newborn’s hemoglobin transitions from HbF to HbA with 70% HbF at 40 weeks’ gestational age to almost 0% at 6 months after birth.
Alex Y. Chung, Dominic S. Carollo
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Abstract Fetal hemoglobin (HbF) is a physiologic variant of the adult hemoglobin (HbA) protein. It is primarily present in the fetus. HbA has a lower oxygen affinity than HbF. A newborn’s hemoglobin transitions from HbF to HbA with 70% HbF at 40 weeks’ gestational age to almost 0% at 6 months after birth.
Alex Y. Chung, Dominic S. Carollo
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5‐azacytidine and fetal hemoglobin
American Journal of Hematology, 1984AbstractThe evidence that 5‐azacytidine stimulates the production of Hb F and F cells in baboon and man is reviewed. The mechanism of this effect is not entirely clear, but 5‐azacytidine produces hypomethylation of the γ gene at certain sites, and gene expression and DNA hypomethylation are related phenomena in many other systems. Other mechanisms have
P, Heller, J, DeSimone
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Fetal Hemoglobin in Diabetic Patients
Diabetes Care, 1994OBJECTIVE To determine the occurrence of elevated fetal hemoglobin (HbF) among the diabetic population and determine the clinical situation of importance. RESEARCH DESIGN AND METHODS A cross-sectional study was conducted. HbA1c.
L K, Koskinen +2 more
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Fetal hemoglobin as an index of maturity
American Journal of Obstetrics and Gynecology, 1959Abstract The percentage of fetal hemoglobin was determined in 200 samples of cord blood and an attempt was made to correlate this percentage with fetal age and weight. In the term group fetal hemoglobin varied from 55 to 95 per cent with an average of 73.3 per cent. The preterm group averaged 80.6 per cent with a range of 66 to 92 per cent, while the
A B, GERBIE, E J, DECOSTA, R A, REIS
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