Results 221 to 230 of about 72,054 (299)

A common TBP-binding site mutation elevates fetal hemoglobin levels by competitive globin switching change in β-thalassemia. [PDF]

open access: yesBlood Adv
Song M   +13 more
europepmc   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş   +4 more
wiley   +1 more source

Utilization of Fetal Hemoglobin Parameters in Predicting Clinical Severity of Sickle Cell Disease: Retrospective Study From a Tanzanian Cohort. [PDF]

open access: yesJ Blood Med
Haji HM   +16 more
europepmc   +1 more source

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo   +8 more
wiley   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li   +4 more
wiley   +1 more source

A Retrospective Study on Neonatal Jaundice: Early Risk Stratification Value of DAT‐FAT Serological Profiles Confirmed by AET

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This retrospective study aimed to explore the value of DAT‐FAT serological profiles confirmed by AET in classifying neonatal jaundice, evaluating its severity, and guiding clinical management. A total of 915 jaundiced newborns (584 pathological, 331 physiological) admitted from July 2018 to August 2021 were included.
Tian‐Ge Wu   +7 more
wiley   +1 more source

Disrupting ZBTB7A or BCL11A binding sites reactivates fetal hemoglobin in erythroblasts from healthy and β<sup>0</sup>-thalassemia/HbE individuals. [PDF]

open access: yesSci Rep
Wongborisuth C   +11 more
europepmc   +1 more source

FOXC1: A Key Transcription Factor of VSMC‐Derived Foam Cell Formation in Atherosclerotic Plaque Instability

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian   +4 more
wiley   +1 more source

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