Results 211 to 220 of about 115,549 (302)

Disrupting ZBTB7A or BCL11A binding sites reactivates fetal hemoglobin in erythroblasts from healthy and β<sup>0</sup>-thalassemia/HbE individuals. [PDF]

open access: yesSci Rep
Wongborisuth C   +11 more
europepmc   +1 more source

Indocyanine Green–Inspired Polymeric Chromophores With Intrinsic Photostability for Near‐Infrared Imaging

open access: yesSmall, EarlyView.
Indocyanine green (ICG) is widely used for near‐infrared imaging but suffers from poor photostability. Here, an indocyanine green–inspired polymeric NIR chromophore is introduced, exhibiting intrinsically enhanced photostability and biocompatibility.
Su Bin Lee   +14 more
wiley   +1 more source

Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart   +7 more
wiley   +1 more source

Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves   +3 more
wiley   +1 more source

The histone deacetylase inhibitor CT-101 flips the switch to fetal hemoglobin expression in sickle cell disease mice. [PDF]

open access: yesPLoS One
Takezaki M   +9 more
europepmc   +1 more source

Free Fetal DNA Testing to Guide Early Intervention in the Management of the Kell Alloimmunized Pregnancy

open access: yes
Prenatal Diagnosis, EarlyView.
Kenneth J. Moise Jr   +3 more
wiley   +1 more source

Risk of minor congenital heart defect in infants conceived via assisted reproductive technology: cohort study from the Copenhagen Baby Heart Study

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective Infertility affects up to 20% of couples in high‐income countries, which has led to an increased use of assisted reproductive technology (ART). While previous studies have linked ART to a higher risk of major congenital heart defects (CHD), less is known about the associated risk of minor CHD.
F. Kyhl‐Svart   +16 more
wiley   +1 more source

A replication study of novel fetal hemoglobin-associated genetic variants in sickle cell disease-only cohorts. [PDF]

open access: yesHum Mol Genet
Ilboudo Y   +13 more
europepmc   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

open access: yesVIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu   +10 more
wiley   +1 more source

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