Results 191 to 200 of about 115,549 (302)

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Fetal hemoglobin enables malaria parasite growth in sickle cells but augments production of transmission stage parasites. [PDF]

PLoS One
Lavazec C, Loucoubar C, Dupuy F, Bureau JF, Casadémont I, Gonçalves B, Thein SL, Lathrop M, Laurance S, Roussel C, Le Van Kim C, Colin Y, De Montalembert M, Sakuntabhai A, Paul RE.   +14 more
europepmc   +1 more source

Studies on Yak Hemoglobin (Bos Grunniens, Bovidae) [PDF]

, 1985
Braunitzer, G., Lalthantluanga, R., Wiesner, Henning   +2 more
core  

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source

Dissecting the epigenetic regulation of the fetal hemoglobin genes to unravel a novel therapeutic approach for β-hemoglobinopathies. [PDF]

Nucleic Acids Res
Amistadi S, Fontana L, Magnoni C, Felix T, Charvin MK, Martinucci P, Gautier C, Greau L, Bessières B, Antoniou P, Romano O, Allemand E, Mussolino C, Miccio A.   +13 more
europepmc   +1 more source

Correlation of changes in circulating levels of hypoxia-induced factor-1α, erythropoietin, and cell-free fetal hemoglobin with feto-maternal pregnancy outcomes. [PDF]

Braz J Med Biol Res
Mohamed AA, Albahlol IA, Alzarea EA, Alshaikh ABA, Edris FE, Abdel-Tawab MS, El-Metwally TH.   +6 more
europepmc   +1 more source

The microchromatographic estimation of fetal hemoglobin levels in hereditary persistence of fetal hemoglobin.

Clinical Chemistry, 1984
P Mohorn, A E Neely, D Y Parnell, C R Baisden, M H Jonah, J S Krauss   +5 more
openaire   +1 more source

Neuroimaging Findings and Risk Factors for Brain Injury in Foetuses Treated for Anaemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Characterize neuroimaging findings in foetuses with anaemia and identify associated risk factors. Methods Retrospective cohort study of pregnancies with foetal anaemia (defined as haemoglobin > 2 standard deviations below the gestational age mean) confirmed by foetal blood sampling (FBS) and treated with intrauterine transfusion (IUT)
Laurence Sophie Carmant, Carlos Robles, Seungwoo Lee, Prakesh S. Shah, Greg Ryan, Elka Miller, Shiri Shinar   +6 more
wiley   +1 more source

A new target for fetal hemoglobin reactivation

Haematologica, 2019
Angela Rivers, Robert Molokie, Donald Lavelle   +2 more
doaj   +1 more source

A tetramer of BCL11A is required for stable protein production and fetal hemoglobin silencing. [PDF]

Science
Zheng G, Yin M, Mehta S, Chu IT, Wang S, AlShaye A, Drainville K, Buyanbat A, Bienfait F, Tenglin K, Zhu Q, Orkin SH.   +11 more
europepmc   +1 more source