Results 191 to 200 of about 114,148 (300)

Association of early postnatal decline in fetal hemoglobin with bronchopulmonary dysplasia in very low birth weight infants: a cohort study. [PDF]

BMC Pregnancy Childbirth
Niu C, Wu H, Lin Z, Li X, Dang D, Mu X.
europepmc   +1 more source

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source

A common TBP-binding site mutation elevates fetal hemoglobin levels by competitive globin switching change in β-thalassemia. [PDF]

Blood Adv
Song M, Wei X, Luo H, Wang J, Ye Y, Qin L, Niu C, Long Y, Wang X, Shao C, Yu M, Gu F, Zhang X, Xu X.   +13 more
europepmc   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li, Xue Wang, Wei Du, Qian Li, Hong‐Ping Cui   +4 more
wiley   +1 more source

A prime editing strategy to rewrite the γ-globin promoters and reactivate fetal hemoglobin for sickle cell disease.

Blood
Chalumeau A, Bou Dames M, Fontana L, Amistadi S, Antoniou P, Loganathan P, Mombled M, Corre G, Peterka M, Amendola M, Giovannangeli C, Maresca M, Miccio A, Brusson M.   +13 more
europepmc   +1 more source

Utilization of Fetal Hemoglobin Parameters in Predicting Clinical Severity of Sickle Cell Disease: Retrospective Study From a Tanzanian Cohort. [PDF]

J Blood Med
Haji HM, Urio F, Nkya S, Chamba C, Nasser A, Lyimo M, Ally M, Mawalla W, Jonathan A, Kidenya B, Mutagonda R, Chirande L, Ruggajo P, Ambrose E, Metta E, Balandya E, Makani J.   +16 more
europepmc   +1 more source

Studies on Yak Hemoglobin (Bos Grunniens, Bovidae) [PDF]

, 1985
Braunitzer, G., Lalthantluanga, R., Wiesner, Henning   +2 more
core  

Polyglycerol‐Based Lipids: A Next‐Generation Alternative to PEG in Lipid Nanoparticles for Advanced Drug Delivery Systems

Macromolecular Rapid Communications, EarlyView.
Linear polyglycerol is proposed as a PEG‐alternative in mRNA‐loaded lipid nanoparticles to limit activation of anti‐PEG antibodies and reduce immunogenicity. Resulting nanoparticles may provide similar gene delivery capabilities, while preventing binding of anti‐PEG antibodies compared to PEGylated counterparts.
Yara Ensminger, Rashmi Rashmi, Michael Karimov, Gideon Nölte, Markus Hafke, Ann‐Cathrin Schmitt, David Díaz‐Oviedo, Johannes Köbberling, Rainer Haag   +8 more
wiley   +1 more source

A new target for fetal hemoglobin reactivation

Haematologica, 2019
Angela Rivers, Robert Molokie, Donald Lavelle   +2 more
doaj   +1 more source

Fetal Hemoglobin in Preterm Infants After Resuscitation with Immediate Cord Clamping, Delayed Cord Clamping, or Cord Milking. [PDF]

Children (Basel)
Dani C, Remaschi G, Ulivi M, Monti N, Pratesi S.   +4 more
europepmc   +1 more source