Results 181 to 190 of about 114,148 (300)

Health Biomarkers of Pesticide Exposure in Rural Populations of Santa Fe, Argentina: Oxidative Stress and Genotoxicity

Journal of Applied Toxicology, EarlyView.
ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara, Carlina Leila Colussi, Lucía Magdalena Odetti, Damián Marino, María Fernanda Simoniello   +4 more
wiley   +1 more source

Dissecting the epigenetic regulation of the fetal hemoglobin genes to unravel a novel therapeutic approach for β-hemoglobinopathies. [PDF]

Nucleic Acids Res
Amistadi S, Fontana L, Magnoni C, Felix T, Charvin MK, Martinucci P, Gautier C, Greau L, Bessières B, Antoniou P, Romano O, Allemand E, Mussolino C, Miccio A.   +13 more
europepmc   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Fetal hemoglobin enables malaria parasite growth in sickle cells but augments production of transmission stage parasites. [PDF]

PLoS One
Lavazec C, Loucoubar C, Dupuy F, Bureau JF, Casadémont I, Gonçalves B, Thein SL, Lathrop M, Laurance S, Roussel C, Le Van Kim C, Colin Y, De Montalembert M, Sakuntabhai A, Paul RE.   +14 more
europepmc   +1 more source

Recent Advances in Thalassemia Research: A Comprehensive Assessment From Diagnostic Technologies to Clinical Treatment

Journal of Clinical Laboratory Analysis, EarlyView.
Thalassemia, a common hereditary blood disorder causing impaired globin synthesis and related complications, has seen remarkable progress in recent years due to advancements in genomics and molecular biology. Researchers have identified various gene variants related to thalassemia and improved clinical diagnostic methods, including new genetic testing ...
Chaoqiong Zhou, Ting Chen, Ying Huang, Huali Wang, Dahai He, Feng Wu, Yan Zhang, Lirui Kong   +7 more
wiley   +1 more source

Correlation of changes in circulating levels of hypoxia-induced factor-1α, erythropoietin, and cell-free fetal hemoglobin with feto-maternal pregnancy outcomes. [PDF]

Braz J Med Biol Res
Mohamed AA, Albahlol IA, Alzarea EA, Alshaikh ABA, Edris FE, Abdel-Tawab MS, El-Metwally TH.   +6 more
europepmc   +1 more source

Diagnosis of Amniotic Sac Herniation Into Uterine Dehiscence Using Combined Ultrasound and Magnetic Resonance Imaging—A Rare Complication Following Fetoscopic Laser Photocoagulation

Journal of Clinical Ultrasound, EarlyView.
Fistula of the anterior uterine wall, through which the amniotic sac of the recipient communicated with the anechoic area outside the uterus (left: ultrasound imaging; right: MRI imaging; star: amniotic sac herniation; arrow: fistula; triangle: bladder).
Ziling Liu, Hongqin Chen, Jie Ruan
wiley   +1 more source

Fetal Hemoglobin Decrease During Voxelotor Treatment. [PDF]

Eur J Haematol
De Luna G, Habibi A, Moutereau S, Martino S, Alhamrouni J, Morel C, Pelinski Y, Zaouali Y, Galactéros F, Bartolucci P.   +9 more
europepmc   +1 more source

Ultrasonography Sliding Sign as a Predictor for Intraabdominal Adhesions in Repeated Cesarean Deliveries: Retrospective Cross Sectional Study

Journal of Clinical Ultrasound, EarlyView.
This retrospective cohort study included 350 individuals who underwent cesarean section. Data from 198 participants who met the inclusion criteria were analyzed. The region below ROC curves for the sliding sign was 0.717 (95% CI: 0.645–0.789). The sensitivity was 58.9%, specificity was 84.6%, positive predictive value (PPV) was 81.7%, negative ...
Can Ata, Ufuk Atlihan, Onur Yavuz, Huseyin Aytug Avsar   +3 more
wiley   +1 more source

Periodontitis during pregnancy: The effect on the gut microbiome and intestinal inflammation

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis has been epidemiologically associated with adverse pregnancy outcomes, but causality remains difficult to establish in humans due to confounding factors. This study uses a controlled murine model to examine the effects of experimentally induced periodontitis on the composition of the gut microbiota and gastrointestinal
Richard Bright, Matthew G. Macowan, Keyuan Tian, Tracy Fitzsimmons, Rebecca L. Wilson, Claire T. Roberts, Claus T. Christophersen, Peter M. Bartold, Stephen P. Kidd, Peter S. Zilm   +9 more
wiley   +1 more source