Neuronal vulnerability to fetal hypoxia-reoxygenation injury and motor deficit development relies on regional brain tetrahydrobiopterin levels. [PDF]
Vasquez-Vivar J +6 more
europepmc +1 more source
EFFECT OF MATERNAL HYPOXIA ON FETAL RAT BRAINS [PDF]
Rebecca Cooper, Robert Vanucci
openalex +1 more source
OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang +10 more
wiley +1 more source
Single-cell transcriptomics of vascularized human brain organoids decipher lineage-specific stress adaptation in fetal hypoxia-reoxygenation injury. [PDF]
Yi S +10 more
europepmc +1 more source
Effect of Hypoxia on RNA Polymerase Activity in Term Fetal Guinea Pig Brain. 254 [PDF]
Ernie Graham +4 more
openalex +1 more source
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu +8 more
wiley +1 more source
Fetal hypoxia and hyperglycemia in the formation of phenytoin-induced cleft lip and maxillary hypoplasia. [PDF]
Ritchie HE +4 more
europepmc +1 more source
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin +19 more
wiley +1 more source
Increased heart rate variability during evolving fetal hypoxia: Be careful during pushing efforts. [PDF]
Descourvieres L +2 more
europepmc +1 more source
A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo +12 more
wiley +1 more source

