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The fetal inflammatory response syndrome
American Journal of Obstetrics and Gynecology, 1998The objective of this study was to determine the frequency and clinical significance of a systemic inflammatory response as defined by an elevated plasma interleukin-6 concentration in fetuses with preterm labor or preterm premature rupture of membranes.Amniocenteses and cordocenteses were performed in 157 patients with preterm labor and preterm ...
Roberto Romero +2 more
exaly +3 more sources
Cerebral palsy and fetal inflammatory response syndrome: a review
Journal of Perinatal Medicine, 2006Cerebral palsy (CP) is the most common cause of severe physical disability in childhood. The precise etiological factor for the development of the majority of cases of CP has not been identified, however, prematurity is considered to be the leading identifiable risk factor. During the last decade, intrauterine infection/inflammation has been identified
Asher Bashiri
exaly +3 more sources
Fetal thymic involution: A sonographic marker of the fetal inflammatory response syndrome
American Journal of Obstetrics and Gynecology, 2006The purpose of this study was to evaluate whether there is a relationship between the sonographic fetal thymus size and the presence of an intrauterine infection in patients with preterm labor.Thirty-one women who had been admitted with preterm labor and intact membranes between 24 and 32 weeks of gestation were included.
Edoardo Di Naro +2 more
exaly +7 more sources
Journal of Maternal-Fetal and Neonatal Medicine, 2002
To determine whether there is a relationship between the presence of histological signs of inflammation in the extraplacental membranes and umbilical cord and the concentrations of fetal plasma interleukin-6 (IL-6).The study examined a cohort of patients who were admitted with preterm labor or preterm premature rupture of the membranes (PROM) and who ...
PACORA P +12 more
exaly +6 more sources
To determine whether there is a relationship between the presence of histological signs of inflammation in the extraplacental membranes and umbilical cord and the concentrations of fetal plasma interleukin-6 (IL-6).The study examined a cohort of patients who were admitted with preterm labor or preterm premature rupture of the membranes (PROM) and who ...
PACORA P +12 more
exaly +6 more sources
Pediatric and Developmental Pathology, 2009
Immature delivery is frequently associated with a maternal-fetal inflammatory response at the placental level. The aims of this study were to determine the prevalence, staging, and grading of histological findings (associated with acute maternal-fetal inflammatory response syndrome) in placentas of immature fetuses and to establish the relationship ...
Rosa B, Fuksman, Nancy G, Mazzitelli
exaly +3 more sources
Immature delivery is frequently associated with a maternal-fetal inflammatory response at the placental level. The aims of this study were to determine the prevalence, staging, and grading of histological findings (associated with acute maternal-fetal inflammatory response syndrome) in placentas of immature fetuses and to establish the relationship ...
Rosa B, Fuksman, Nancy G, Mazzitelli
exaly +3 more sources
American Journal of Obstetrics and Gynecology, 2016
In patients with preterm premature rupture of membranes, intrauterine inflammation and/or infection is frequently present, can lead to fetal inflammatory response syndrome, and is associated with adverse neonatal outcome. Clinical decision making requires balancing the potential benefits of pregnancy prolongation against the risk of intrauterine ...
Maximilian Klar, Wolfgang Schäfer
exaly +4 more sources
In patients with preterm premature rupture of membranes, intrauterine inflammation and/or infection is frequently present, can lead to fetal inflammatory response syndrome, and is associated with adverse neonatal outcome. Clinical decision making requires balancing the potential benefits of pregnancy prolongation against the risk of intrauterine ...
Maximilian Klar, Wolfgang Schäfer
exaly +4 more sources
Therapeutic interventions for fetal inflammatory response syndrome (FIRS)
Seminars in Fetal and Neonatal Medicine, 2020Fetal inflammatory response syndrome (FIRS) is a condition defined by systemic inflammation in the fetus, a rapid increase of pro-inflammatory cytokines into the fetal circulation (including interleukin-1 and interleukin-6), as well as a cellular response (such as increased neutrophils, monocyte/macrophages, and T cells) and the presence of funisitis ...
Ying, Xiong, Pia, Wintermark
openaire +2 more sources
Medico-legal implications of the fetal inflammatory response syndrome
Seminars in Fetal and Neonatal Medicine, 2020Babies who sustain long term neurologic injury and disability are frequent subjects in medical malpractice litigation. In the United States, the tort system enables adjudication of claims through a proscribed system. This paper will review salient elements of the tort system-duty, breach, causation, and damages- and how they apply to encephalopathic ...
Jonathan M, Fanaroff, Steven M, Donn
openaire +2 more sources
Neuroimaging findings associated with the fetal inflammatory response syndrome
Seminars in Fetal and Neonatal Medicine, 2020The fetal inflammatory response syndrome (FIRS) is a condition whereby the fetus mounts an inflammatory response to intrauterine infection/inflammation. Clinical consequences include preterm premature rupture of membranes (PPROM), spontaneous preterm delivery, neonatal sepsis, bronchopulmonary dysplasia, and brain and other organ injury.
Luis F, Goncalves +2 more
openaire +2 more sources