Results 101 to 110 of about 57,194 (288)

Access to prenatal exome sequencing for fetal malformations: A qualitative landscape analysis in the US. [PDF]

Prenat Diagn, 2023
Sahin-Hodoglugil NN, Lianoglou BR, Ackerman S, Sparks TN, Norton ME.   +4 more
europepmc   +1 more source

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

Advanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller, Nicole Vo, Utkarsh, Ivan Sokirniy, Justin Pritchard, Benjamin S. Freedman, Scott H. Medina   +6 more
wiley   +1 more source

Arnold-chiari In A Fetal Rat Model Of Dysraphism.

, 2015
Dysraphism is a defect in neural tube development, leading to dysplastic growth of the spinal cord and meninges. Myelomeningocele (MM) is just one of its forms.
Weber Guimarães Barreto, Maria, Guimarães Bittencourt, Daniel, Barini, Ricardo, Sbragia, Lourenço, Violin Pereira, Luis A, Ferro, Marcelo M   +5 more
core   +2 more sources

A study on the correlation between MTHFR and folic acid combined with trace elements for the prevention of fetal malformations in the first trimester of pregnancy. [PDF]

Medicine (Baltimore), 2023
Zhang H, Pan J, Jiang H, Xiong X, Huang L, Liu X, Wangzi WX, Chen L.   +7 more
europepmc   +1 more source

A critical review of benefits and limitations of magnetic resonance imaging as a complementary method in the diagnosis of fetal malformations

, 2008
OBJECTIVE: The present study was aimed at evaluating by means of magnetic resonance imaging a series of fetuses with sonographic diagnosis of malformation, establishing the diagnostic benefits and limitations of fetal magnetic resonance imaging as ...
Szejnfeld, Jacob [UNIFESP], Ximenes, Andréa Regina Da Silveira, Ximenes, Renato Luis Da Silveira [UNIFESP], Zanderigo, Valdir   +3 more
core   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Fetal posterior fossa malformations: review of the current knowledge

, 2019
Ultrasound diagnosis of posterior fossa malformations in the prenatal period is a challenge, having major implications for the counseling and follow-up of pregnant women. The purpose of this study was to review aspects of the ultrasound evaluation of the
Edward Araujo Júnior (7291583), Hérbene Jose Figuinha Milani (8048828), Carlos Alberto Raimundo Baldo (8048834), Antonio Fernandes Moron (4772553), Renato Luis da Silveira Ximenes (8048831), Enoch Quindere de Sá Barreto (6699650)   +5 more
core   +1 more source

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

Advanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan, Xuelin Wang, Zhongyao Chen, Shuo Wang, Weining Gao, Ziyi Chen, Runyang Li, Cheng Hao, Lei Zhang, Qiongqiong Zhang, Ke Zhang, Mei Yu, Qian Liu, Jingxuan Wang, Huiping Li, Simpkins Fiona, Jing Liu, Qiang Liu, Peng Liu, Yawei Hu   +19 more
wiley   +1 more source

Fetal malformations associated with exposure to mycophenolic acid during the first trimester. [PDF]

Int J Pediatr Adolesc Med, 2022
Khan F, Syed F, AbdulMuthalib H, Dammas N, Al Alaiyan S, Al Hazzani F, Kattan A, Bin Jabr M, Bin Manea A, Almidani E.   +9 more
europepmc   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source