Fetal Membrane Epigenetics [PDF]
Frontiers in Physiology, 2020 The characteristics of fetal membrane cells and their phenotypic adaptations to support pregnancy or promote parturition are defined by global patterns of gene expression controlled by chromatin structure.
Tamas Zakar +6 more
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Healing Mechanism of Ruptured Fetal Membrane [PDF]
Frontiers in Physiology, 2020 Preterm premature rupture of membranes (pPROM) typically leads to spontaneous preterm birth within several days. In a few rare cases, however, amniotic fluid leakage ceases, amniotic fluid volume is restored, and pregnancy continues until term.
Haruta Mogami, R. Ann Word
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The Role of Danger Associated Molecular Patterns in Human Fetal Membrane Weakening [PDF]
Frontiers in Physiology, 2020 The idea that cellular stress (including that precipitated by stretch), plays a significant role in the mechanisms initiating parturition, has gained considerable traction over the last decade. One key consequence of this cellular stress is the increased
Justin G. Padron +3 more
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Proteomic Study of Fetal Membrane: Inflammation-Triggered Proteolysis of Extracellular Matrix May Present a Pathogenic Pathway for Spontaneous Preterm Birth [PDF]
Frontiers in Physiology, 2020 IntroductionSpontaneous preterm birth (sPTB), which predominantly presents as spontaneous preterm labor (sPTL) or prelabor premature rupture of membranes (PPROM), is a syndrome that accounts for 5–10% of live births annually.
Jing Pan +3 more
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Fetal membrane at the feto-maternal interface: An underappreciated and understudied intrauterine tissue. [PDF]
Placenta Reprod Med, 2022 While most intrauterine tissues are thoroughly studied for their role in pregnancy maintenance and their contribution to labor initiation, the fetal membranes (i.e., amniochorionic membranes) are primarily overlooked.[1,2] The fetal membrane lines the ...
Richardson L, Menon R.
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Generation and characterization of human Fetal membrane and Decidual cell lines for reproductive biology experiments†. [PDF]
Biol Reprod, 2022 Human fetal membrane and maternal decidua parietalis form one of the major feto-maternal interfaces during pregnancy. Studies on this feto-maternal interface is limited as several investigators have limited access to the placenta, and experience ...
Radnaa E +6 more
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Functional role and regulation of permeability-glycoprotein (P-gp) in the fetal membrane during drug transportation. [PDF]
Am J Reprod Immunol, 2022 Na+/H+ exchange regulatory factor‐1 (NHERF‐1) is a class I PDZ (PSD95/Discs‐large/ZO‐1) binding protein involved in cell‐surface expression and stabilization of transporter proteins, including permeability‐glycoprotein (P‐gp) in various cell types. P‐gp,
Kammala A +4 more
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Progesterone receptor membrane components: key regulators of fetal membrane integrity. [PDF]
Biol Reprod, 2021 Pro-pregnancy hormone progesterone (P4) helps to maintain a quiescent status of uterine tissues during gestation. However, P4's functional role in maintaining fetal membrane (amniochorion) integrity remains unclear.
Lozovyy V +3 more
europepmc +2 more sources
Magnetic resonance imaging of the supra-cervical fetal membrane detects an increased risk of prelabor rupture of membranes [PDF]
Frontiers in Endocrinology, 2022 ObjectiveIn 10% of term deliveries and 40% of preterm deliveries, the fetal membrane (FM) ruptures before labor. However, the ability to predict these cases of premature rupture of membranes (PROM) and preterm premature rupture of membranes (PPROM) is ...
Wenxu Qi +12 more
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Formalin-Fixed Paraffin-Embedded (FFPE) samples are not a beneficial replacement for frozen tissues in fetal membrane microbiota research [PDF]
PLoS ONE, 2022 Formalin-Fixed Paraffin-Embedded (FFPE) tissues are routinely collected, archived, and used for clinical diagnosis, including maternal and neonatal health.
Rochelle Hockney +7 more
doaj +3 more sources