Tissue engineering a fetal membrane [PDF]
The aim of this study was to construct an artificial fetal membrane (FM) by combination of human amniotic epithelial stem cells (hAESCs) and a mechanically enhanced collagen scaffold containing encapsulated human amniotic stromal fibroblasts (hASFs ...
Adam M. Squires+11 more
core +8 more sources
Sodium Hydrogen Exchanger Regulatory Factor-1 (NHERF1) Regulates Fetal Membrane Inflammation. [PDF]
The fetal inflammatory response, a key contributor of infection-associated preterm birth (PTB), is mediated by nuclear factor kappa B (NF-kB) activation.
Kammala AK+5 more
europepmc +2 more sources
Fetal membrane imaging: current and future perspectives—a review [PDF]
Fetal membrane providing mechanical support and immune protection for the growing fetus until it ruptures during parturition. The abnormalities of fetal membrane (thickening, separation, etc.) are related to adverse perinatal outcomes such as premature ...
Dan Wu+19 more
doaj +2 more sources
In vivo Assessment of Supra-Cervical Fetal Membrane by MRI 3D CISS: A Preliminary Study [PDF]
In approximately 8% of term births and 33% of pre-term births, the fetal membrane (FM) ruptures before delivery. In vitro studies of FMs after delivery have suggested the series of events leading to rupture, but no in vivo studies have confirmed this ...
Wenxu Qi+19 more
doaj +2 more sources
Interleukin (IL)-6: A Friend or Foe of Pregnancy and Parturition? Evidence From Functional Studies in Fetal Membrane Cells. [PDF]
Objective Protection of the fetus within the amniotic sac is primarily attained by remodeling fetal membrane (amniochorion) cells through cyclic epithelial to mesenchymal and mesenchymal to epithelial (EMT and MET) transitions.
Omere C+5 more
europepmc +2 more sources
Compensatory fetal membrane mechanisms between biglycan and decorin in inflammation. [PDF]
Preterm premature rupture of fetal membranes (PPROM) is associated with infection, and is one of the most common causes of preterm birth. Abnormal expression of biglycan and decorin, two extracellular matrix proteoglycans, leads to preterm birth and ...
Aron, Abraham+4 more
core +3 more sources
A collagen plug with shape memory to seal iatrogenic fetal membrane defects after fetoscopic surgery [PDF]
Iatrogenic preterm premature rupture of fetal membranes (iPPROM) after fetal surgery remains a strong trigger for premature birth. As fetal membrane defects do not heal spontaneously and amniotic fluid leakage and chorioamniotic membrane separation may ...
Rob T.C. Meuwese+7 more
doaj +2 more sources
Immunobiology of Acute Chorioamnionitis [PDF]
Acute chorioamnionitis is characterized by neutrophilic infiltration and inflammation at the maternal fetal interface. It is a relatively common complication of pregnancy and can have devastating consequences including preterm labor, maternal infections,
Monica Cappelletti+2 more
doaj +3 more sources
Function and failure of the fetal membrane: Modelling the mechanics of the chorion and amnion.
The fetal membrane surrounds the fetus during pregnancy and is a thin tissue composed of two layers, the chorion and the amnion. While rupture of this membrane normally occurs at term, preterm rupture can result in increased risk of fetal mortality and ...
Stefaan W Verbruggen+3 more
doaj +2 more sources
Human parturition is an inflammatory process that involves both fetal and maternal compartments. The precise immune cell interactions have not been well delineated in human uterine tissues during parturition, but insights into human labor initiation have
Ramkumar Menon+2 more
doaj +2 more sources