Antimicrobial Activity of Human Fetal Membranes: From Biological Function to Clinical Use [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 The fetal membranes provide a supportive environment for the growing embryo and later fetus. Due to their versatile properties, the use of fetal membranes in tissue engineering and regenerative medicine is increasing in recent years.
Taja Železnik Ramuta +3 more
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Functional Genomics of Healthy and Pathological Fetal Membranes [PDF]
Frontiers in Physiology, 2020 Premature preterm rupture of membranes (PPROM), rupture of fetal membranes before 37 weeks of gestation, is the leading identifiable cause of spontaneous preterm births.
Sarah J. Cunningham +9 more
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New approaches suggest term and preterm human fetal membranes may have distinct biomechanical properties [PDF]
Scientific Reports, 2022 Preterm prelabour rupture of membranes is the leading cause of preterm birth and its associated infant mortality and morbidity. However, its underlying mechanism remains unknown. We utilized two novel biomechanical assessment techniques, ball indentation
Sudeshna Bhunia +5 more
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Fetal DNA Causes Sex-Specific Inflammation From Human Fetal Membranes [PDF]
Frontiers in Physiology, 2022 Inflammation is central to the mechanisms of parturition, but the lack of understanding of how it is controlled in normal parturition hampers our ability to understand how it may diverge resulting in preterm birth.
Chelsea A. Saito Reis +5 more
doaj +2 more sources
Possible important roles of galectins in the healing of human fetal membranes [PDF]
Frontiers in Endocrinology, 2022 The fetal membranes healing is a complex and dynamic process of replacing devitalized and missing cellular structures and tissue layers. Multiple cells and extracellular matrices, and cell differentiation, migration and proliferation may participate in ...
Jia-Le Chen +6 more
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Cortisol Regeneration in the Fetal Membranes, A Coincidental or Requisite Event in Human Parturition? [PDF]
Frontiers in Physiology, 2020 The fetal membranes are equipped with high capacity of cortisol regeneration through the reductase activity of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1). The expression of 11β-HSD1 in the fetal membranes is under the feedforward induction by cortisol,
Wang-Sheng Wang +4 more
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Early-Onset Negative Energy Balance in Transition Dairy Cows Increases the Incidence of Retained Fetal Membranes [PDF]
AnimalsThis study investigated the metabolic mechanisms driving physiological functional remodeling in RFM by analyzing plasma biochemical parameters and metabolomic profiles at key peripartum timepoints (21 and 7 d prepartum and 4 h postpartum), integrated ...
Zhihong Zhang +7 more
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Physiological TLR4 regulation in human fetal membranes as an explicative mechanism of a pathological preterm case [PDF]
eLife, 2022 The integrity of human fetal membranes is crucial for harmonious fetal development throughout pregnancy. Their premature rupture is often the consequence of a physiological phenomenon that has been exacerbated. Beyond all the implied biological processes,
Corinne Belville +7 more
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Birth mode is associated with layer-specific mechanical changes in fetal membranes [PDF]
Scientific ReportsRupture of fetal membranes and subsequent full-term birth are prerequisites for neonatal health, and a preterm rupture can lead to life-threatening complications.
Philip Friedrich +11 more
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On the defect tolerance of fetal membranes. [PDF]
Interface Focus, 2019 A series of mechanical experiments were performed to quantify the strength and fracture toughness of human amnion and chorion. The experiments were complemented with computational investigations using a ‘hybrid’ model that includes an explicit representation of the collagen fibre network of amnion. Despite its much smaller thickness, amnion is shown to
Bircher K +7 more
europepmc +6 more sources