Leveraging bioengineering to assess cellular functions and communication within human fetal membranes [PDF]
Journal of Maternal-Fetal and Neonatal Medicine, 2022 The fetal membranes enclose the growing fetus and amniotic fluid. Preterm prelabor rupture of fetal membranes is a leading cause of preterm birth. Fetal membranes are composed of many different cell types, both structural and immune.
Alison J Eastman +2 more
exaly +3 more sources
Lipopolysaccharide induces nitric oxide synthase expression and platelet-activating factor increases nitric oxide production in human fetal membranes in culture [PDF]
Reproductive Biology and Endocrinology, 2004 Background Platelet-activating factor and nitric oxide may be involved in the initiation of human labour as inflammatory mediators. The aim of this study was to test whether platelet-activating factor and lipopolysaccharide were able to induce nitric ...
Seyffarth Gunter +5 more
doaj +2 more sources
Evaluation of the best time for manual removal of retained fetal membranes in the cow [PDF]
Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2007 The syndrome of retained fetal membranes (RFM) is an important problem in dairy cattle industry in Iran and most other countries. However, the syndrome has not been defined precisely nor specific recommendations have been suggested for its management ...
H Hamali, H Karimi
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Fetal Membrane Epigenetics [PDF]
Frontiers in Physiology, 2020 The characteristics of fetal membrane cells and their phenotypic adaptations to support pregnancy or promote parturition are defined by global patterns of gene expression controlled by chromatin structure. Heritable epigenetic chromatin modifications that include DNA methylation and covalent histone modifications establish chromatin regions permissive ...
Tamas Zakar +6 more
openaire +3 more sources
Application of Fetal Membranes and Natural Materials for Wound and Tissue Repair. [PDF]
Int J Mol SciThe human fetal membrane is a globally accepted biological biomaterial for wound and tissue repair and regeneration in numerous fields, including dermatology, ophthalmology, and more recently orthopedics, maxillofacial and oral surgery, and nerve ...
Rouzaire M +3 more
europepmc +2 more sources
A collagen plug with shape memory to seal iatrogenic fetal membrane defects after fetoscopic surgery
Bioactive Materials, 2023 Iatrogenic preterm premature rupture of fetal membranes (iPPROM) after fetal surgery remains a strong trigger for premature birth. As fetal membrane defects do not heal spontaneously and amniotic fluid leakage and chorioamniotic membrane separation may ...
Rob T.C. Meuwese +7 more
doaj +1 more source
Stretch Causes Cell Stress and the Downregulation of Nrf2 in Primary Amnion Cells
Biomolecules, 2022 Nuclear-factor-E2-related factor 2 (Nrf2) is a key transcription factor for the regulation of cellular responses to cellular stress and inflammation, and its expression is significantly lower after spontaneous term labor in human fetal membranes ...
Justin Gary Padron +3 more
doaj +1 more source
The citrus flavone nobiletin reduces pro-inflammatory and pro-labour mediators in fetal membranes and myometrium: implications for preterm birth. [PDF]
PLoS ONE, 2014 Spontaneous preterm birth is the leading cause of infant death and of neurological disabilities in survivors. A significant proportion of spontaneous preterm births are associated with infection.
Carrington J Morwood, Martha Lappas
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Effect of silibinin in reducing inflammatory pathways in in vitro and in vivo models of infection-induced preterm birth. [PDF]
PLoS ONE, 2014 Infection-induced preterm birth is the largest cause of infant death and of neurological disabilities in survivors. Silibinin, from milk thistle, exerts potent anti-inflammatory activities in non-gestational tissues.
Ratana Lim +3 more
doaj +1 more source
Frontiers in Physiology, 2020 IntroductionSpontaneous preterm birth (sPTB), which predominantly presents as spontaneous preterm labor (sPTL) or prelabor premature rupture of membranes (PPROM), is a syndrome that accounts for 5–10% of live births annually.
Jing Pan +3 more
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