Results 41 to 50 of about 4,947,559 (270)
A mixed‐methods evaluation of continuous electronic fetal monitoring for an extended period
Acta Obstetricia et Gynecologica Scandinavica, 2018 Continuous fetal monitoring is used to objectively record the fetal heart rate and fetal activity over an extended period of time; however, its feasibility and acceptability to women is currently unknown.
Alexandra Crawford +8 more
semanticscholar +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Signals, 2021 During the pregnancy, fetal electrocardiogram (FECG) is deployed to analyze fetal heart rate (FHR) of the fetus to indicate the growth and health of the fetus to determine any abnormalities and prevent diseases. The fetal electrocardiogram monitoring can
Geetika Aggarwal, Yang Wei
doaj +1 more source
National survey of routines for intrapartum fetal monitoring in Norway
Acta Obstetricia et Gynecologica Scandinavica, 2018 This study describes clinical routines for intrapartum fetal monitoring in Norway and compliance with national clinical recommendations.
A. Kaasen +4 more
semanticscholar +1 more source
Wireless, remote solution for home fetal and maternal heart rate monitoring.
American Journal of Obstetrics & Gynecology MFM, 2020 BACKGROUND Access to prenatal care can be challenging due to physician shortages and rural geography. The multiple prenatal visits performed to collect basic fetal measurements lead to significant patient burden as well.
Muhammad Mhajna +8 more
semanticscholar +1 more source
Methods for Monitoring Risk of Hypoxic Damage in Fetal and Neonatal Brains: A Review
Fetal Diagnosis and Therapy, 2021 Fetal, perinatal, and neonatal asphyxia are vital health issues for the most vulnerable groups in human beings, including fetuses, newborns, and infants.
Liaisan Uzianbaeva +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Non-Adaptive Methods for Fetal ECG Signal Processing: A Review and Appraisal
Sensors, 2018 Fetal electrocardiography is among the most promising methods of modern electronic fetal monitoring. However, before they can be fully deployed in the clinical practice as a gold standard, the challenges associated with the signal quality must be solved.
Rene Jaros +2 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source