Results 131 to 140 of about 1,852,080 (263)

Inequality and Infant and Childhood Mortality in the United States in the Twentieth Century [PDF]

open access: yes
This paper deals with the issue of using infant and childhood mortality as an indicator of inequality. The case is that of the United States in the 20th century. Using microdata from the 1900 and 1910 Integrated Public Use Microsamples (IPUMS), published
Michael R. Haines
core  

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

open access: yesAdvanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng   +13 more
wiley   +1 more source

Statistics on spatial scanning: methodological tutorial with application to fetal mortality in Brazil, 2014-2023

open access: yesRevista Brasileira de Saúde Materno Infantil
Objectives: to develop a systematic tutorial on the application of statistics on spatial scanning using the discrete Poisson model, covering its theoretical assumptions to its analytical implementation for the detection of spatial clusters of risk for ...
Indianara Maria de Barros Canuto   +3 more
doaj   +2 more sources

Toxic exposure in America: estimating fetal and infant health outcomes [PDF]

open access: yes
We examine the effect of toxic exposure on U.S. infant and fetal mortality rates between 1989 and 2002 from toxic pollution released by facilities reporting to the Toxic Release Inventory (TRI).
Linda T.M. Bui   +2 more
core  

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

open access: yesAdvanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu   +10 more
wiley   +1 more source

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

open access: yesAdvanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan   +9 more
wiley   +1 more source

Proceedings of the International Collaborative Effort on Perinatal and Infant Mortality, Volume 1; papers presented at the International Symposium on Perinatal and Infant Mortality, 1984 ; Bethesda, Maryland [PDF]

open access: yes
On August 6-9, 1984, the International Collaborative Effort (ICD) on Perinatal and Infant Mortality of the National Center for Health Statistics (NCHS) convened an International Symposium for the purpose of coordinating research activities of NCHS with ...

core  

Engineering Synergistic Intra‐/Intermolecular Conformational Locking via Side‐Chain Branching: A β‐Sheet‐Inspired Strategy for Planar NIR‐II Phototheranostic Aggregates

open access: yesAdvanced Science, EarlyView.
A bio‐inspired side‐chain branching strategy is developed to orchestrate a dual noncovalent conformational locking (NoCL) network, enabling the construction of perfectly planar NIR‐II phototheranostic aggregates. Such structural precision maximizes light‐harvesting efficiency and optimizes exciton dynamics, ensuring synchronized enhancements in NIR‐II ...
Cheng Lu   +11 more
wiley   +1 more source

Immediate Growth Control in Response to Boiling Histotripsy is Prognostic for Intratumoral Immune Activation

open access: yesAdvanced Science, EarlyView.
Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger   +8 more
wiley   +1 more source

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