Results 51 to 60 of about 3,706,561 (264)

Fetal alcohol spectrum disorders: strategies to address information gaps [PDF]

, 2014
Fetal Alcohol Spectrum Disorders (FASD) is emerging as a public health issue in Australia. Health-care providers and policy makers need accurate and timely data in a useable format to monitor and prevent FASD.

core  

Maternal and Perinatal Outcome in Women with Congenital Heart Disease: A DescriptiveCross-sectional Study

Journal of Nepal Medical Association
Introduction: Untreated and residual congenital heart disease in a pregnant woman is concerning for both the mother and the baby. Early diagnosis and management are imperative to ensure survival of both mother and the baby.
Pooja Paudyal, Asmita Ghimire, Bashu Dev Parajuli, Prabhat Khakural   +3 more
doaj   +1 more source

A simple score to predict fetal outcomes in gestational diabetes mellitus

Biomedical Journal, 2015
Background: Strict glycemic control is critical in preventing adverse maternal and fetal outcomes with gestational diabetes mellitus (GDM), but frequently results in recurrent maternal hypoglycemia and is often impracticable.
Kushal Naha, Sowjanya Naha, Vinay R Pandit, Shubha Seshadri   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Role of Genes and Environment on Fetal Growth [PDF]

, 2014
Fetal growth is influenced by the in utero environment and genetic factors inherited from both parents. Poor fetal growth leading to low birth weight is associated with insulin resistance and type-2 diabetes in later life.
Hillman, SL
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Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Fetal alcohol spectrum disorders: a review of interventions for prevention and management in Indigenous communities [PDF]

, 2015
This resource sheet provides estimates on the prevalence of fetal alcohol spectrum disorders in the general and Indigenous populations of Australia, and reviews the local and international evidence on the effectiveness of programs that aim to prevent or ...
Closing the Gap Clearinghouse
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Vitamins and Perinatal Outcomes Among HIV-Negative Women in Tanzania. [PDF]

, 2007
Prematurity and low birth weight are associated with high perinatal and infant mortality, especially in developing countries. Maternal micronutrient deficiencies may contribute to these adverse outcomes. In a double-blind trial in Dar es Salaam, Tanzania,
Msamanga, G.I, Petraro, Paul, Willett, Walter C, Hertzmark, Ellen, Urassa, W., Urassa, Willy, Hertzmark, E., Fawzi, W.W, Spiegelman, D., Petraro, P., Msamanga, Gernard I, Fawzi, Wafaie W, Willett, W.C, Spiegelman, Donna   +13 more
core   +1 more source

Pregnancy and autoimmune hepatitis

Annals of Hepatology, 2006
Autoimmune hepatitis is a rare condition that is more common among women than men. An association between pregnancy and autoimmune hepatitis is rare. This clinical scenario requires the gastroenterologist and hepatologist to have a profound knowledge of ...
Misael Uribe, Norberto C. Chavez-Tapia, Nahum Mendez-Sanchez   +2 more
doaj   +1 more source