Results 181 to 190 of about 1,024,043 (307)

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Maternal gut microbiota mediates prenatal stress-induced fetal blood‒brain barrier dysfunction. [PDF]

Gut Microbes
Wang X, Zhou FY, Wu T, Duan C, Luo X, Meng Y, Huang HF, Wu YT.   +7 more
europepmc   +1 more source

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

Advanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato, Haishuo Guan, Bianca M. Carrara, Mira Jacobs, Matteo Monticelli, Lukas Moser, Thomas Moragues, Andrew J. deMello, Tomaso Zambelli, Martin Ehrbar   +9 more
wiley   +1 more source

Interplay between flaviviruses and the interferon response: mechanisms of immune evasion and therapeutic implications. [PDF]

Front Pharmacol
Han J, Yin Y, Yuan J.
europepmc   +1 more source

Inactivating SARS‐CoV‐2 Virus with MOF‐Composites as Smart Face Masks

Advanced Functional Materials, EarlyView.
In situ preparation and functionalization of MOF@Cotton fabrics as smart face masks for the immobilization of proteins and inactivation viruses, such as SARS‐CoV‐2. Abstract The significant impact of the SARS‐CoV‐2 (COVID‐19) pandemic outbreak on people's lives has highlighted the urgent need for effective personal protective equipment.
Romy Ettlinger, Aamod V. Desai, Hau Lam Jody Cheong, Louise L. Major, Terry K. Smith, Aaron B. Naden, Jane Hilton, Catherine S. Adamson, A. Robert Armstrong, Russell E. Morris   +9 more
wiley   +1 more source

Prenatal Aflatoxin B₁ Exposure: A Review of Pathogenesis and Impact on Fetal Skeletal Development and Ossification. [PDF]

Toxins (Basel)
Montenegro GP, Batista da Silva JV, Ali S, Ullah S, Freire LGD, Oliveira CAF, Ramalho LNZ.   +6 more
europepmc   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

TRANSPORT OF PROTEINS ACROSS THE FETAL MEMBRANES

Cold Spring Harbor Symposia on Quantitative Biology, 1954
openaire   +2 more sources

Conserved gene expression patterns in the placenta underlie pregnancy complications associated with hypoxia in mice and humans. [PDF]

Cell Mol Life Sci
Siragher EJ, Higgins JS, Vaughan OR, Fowden AL, Sferruzzi-Perri AN.   +4 more
europepmc   +1 more source

Protein network analysis reveals selectively vulnerable regions and biological processes in FTD [PDF]

, 2018
Karch, Celeste M., Ofori-Kuragu, Aaron, Wen, Natalie   +2 more
core   +1 more source