Placenta-Driven Evolution: Viral Gene Acquisition and <i>PEG10</i>'s Essential Roles in Eutherian Placenta. [PDF]
BiomoleculesShiura H +3 more
europepmc +1 more source
Controlling 3D Contractility via Engineered Fibrous Hydrogel Composites
Advanced Functional Materials, EarlyView.A tunable composite contractile assembly (CCA) is developed that can permit or resist contraction without changing cell‐adhesion and density, unlike collagen whose inherent coupling of these ECM cues limits its use as a platform in contractility studies.
Karen L. Xu +7 more
wiley +1 more source
Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerative Healing. [PDF]
Biology (Basel)Niti A, Kouzi-Koliakou K, Michopoulou A.
europepmc +1 more source
Advanced Functional Materials, EarlyView.Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid +6 more
wiley +1 more source
Mechanisms and Therapeutic Implications of Microbiome-Mediated Immune Dysregulation in Recurrent Pregnancy Loss and Implantation Failure. [PDF]
Am J Reprod ImmunolBahia W +3 more
europepmc +1 more source
Cardiac‐Derived ECM Microspheres for Enhanced hiPSC‐CMs Maturation
Advanced Functional Materials, EarlyView.Cardiac extracellular matrix microspheres derived from decellularized porcine heart provide a biomimetic 3D microenvironment for human induced pluripotent stem cell–derived cardiomyocytes (hiPSC‐CMs). This platform supports short‐ and long‐term culture, enhances structural organization, and promotes electrophysiological and functional maturation of ...
Jiazhu Xu +9 more
wiley +1 more source
Adhesion molecules in the maternal-fetal interface in healthy pregnancies and preeclampsia. [PDF]
Acta Obstet Gynecol ScandFrisch IK +4 more
europepmc +1 more source
Dense Nanofibrillar Collagen–Silica Hybrids with High Strength and ECM‐Mimetic Tissue Integration
Advanced Functional Materials, EarlyView.Dense nanofibrillar collagen–silica hybrids are engineered by synchronizing collagen fibrillogenesis with silica condensation, producing printable scaffolds that unexpectedly approach native extracellular matrix organization and strength. These cell‐free constructs guide endogenous cell‐infiltration, enable localized matrix remodeling, and integrate ...
Norein Norein +7 more
wiley +1 more source
3D‐Printed Porous Hydroxyapatite Formed via Enzymatic Mineralization
Advanced Functional Materials, EarlyView.Bone combines lightness, strength, and the ability to heal, inspiring new materials design. This work introduces a room‐temperature, enzyme‐mediated 3D printing method to create porous hydroxyapatite scaffolds. The process avoids energy‐intensive sintering, preserves bioactivity, and allows control over porosity and mineralization.
Francesca Bono +6 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian +5 more
wiley +1 more source