Results 221 to 230 of about 7,077,080 (366)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Deciphering Roles of Placental Endoplasmic Reticulum Stress in Complicated Pregnancies and Beyond: The Power of Mouse Models. [PDF]

Cells
Yung HW, Yung YN, Burton GJ, Charnock-Jones DS.   +3 more
europepmc   +1 more source

Estrogen Suppresses Interaction of Melanocortin 2 Receptor and Its Accessory Protein in the Primate Fetal Adrenal Cortex [PDF]

, 2016
Jeffery S. Babischkin, Graham W. Aberdeen, Gerald J. Pepe, Eugene D. Albrecht   +3 more
openalex   +1 more source

Nuclear proteins that bind the human gamma-globin gene promoter: alterations in binding produced by point mutations associated with hereditary persistence of fetal hemoglobin

Molecular and Cellular Biology, 1988
D. Gumucio, K. Rood, T. Gray, M. Riordan, C. Sartor, F. Collins   +5 more
semanticscholar   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Presence of SARS-CoV-2 in fetal organs via intraamniotic infection. [PDF]

Nat Commun
Wu S, Tang L, Liu Z, Wu M, He X, Shan S, Zhou Y, Lin K, Xu Q, Tan S, Zhang Z, Xu Y, Wang C, Zhu F, Wei Z, Jin L.   +15 more
europepmc   +1 more source

Protein network analysis reveals selectively vulnerable regions and biological processes in FTD [PDF]

, 2018
Karch, Celeste M., Ofori-Kuragu, Aaron, Wen, Natalie   +2 more
core   +1 more source

Embryonic stem cells and nuclear transfer strategies - Present state and future prospects [PDF]

, 2000
Beier, Henning M., Wobus, Anna M., Wolf, Eckhard   +2 more
core   +1 more source

Mineral and collagen-binding proteins of fetal calf bone.

Journal of Biological Chemistry, 1981
J. Termine, A. Belcourt, K. Conn, H. Kleinman   +3 more
semanticscholar   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source