Results 121 to 130 of about 3,436,268 (369)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Autonomous Magnetic Navigation in Endoscopic Image Mosaics

Advanced Science
Endoscopes navigate within the human body to observe anatomical structures with minimal invasiveness. A major shortcoming of their use is their narrow field‐of‐view during navigation in large, hollow anatomical regions.
Michelle Mattille, Quentin Boehler, Jonas Lussi, Nicole Ochsenbein, Ueli Moehrlen, Bradley J. Nelson   +5 more
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Effect of very preterm delivery on outcomes following in utero spina bifida repair

Pregnancy
Objective In utero fetal spina bifida repair decreases the risk for cerebrospinal fluid (CSF) diversion including ventriculoperitoneal (VP) shunt placement, reverses hindbrain herniation, and improves motor function with a higher likelihood of ...
Michael V. Zaretsky, Jagruti Anadkat, Kelly A. Bennett, Yair J. Blumenfeld, Chris Buchanan, Caitlin Clifford, Timothy Crombleholme, Samer Elbabaa, Stephen P. Emery, William H. Goodnight, Hanmin Lee, Joseph B. Lillegard, Foong‐Yen Lim, Francois I. Luks, Virginia Lijewski, Jena L. Miller, Ueli Moehrlen, Julie Moldenhauer, Anita J. Moon‐Grady, Mauro Schenone, Daniel W. Skupski, Aimen F. Shaaban, Kuojen Tsao, Tim Van Mieghem, Amy J. Wagner   +24 more
doaj   +1 more source

BUSM Dean's report [PDF]

, 1999
Reports from the Office of the Dean, Boston University School of ...
Office of the Dean, Boston University School of Medicine
core  

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

A Closer Look at the Global Management of Spina Bifida: The Implementation of Endoscopic Third Ventriculostomy in the Treatment of Spina Bifida-Related Hydrocephalus in Africa [PDF]

, 2018
Spina bifida, specifically myelomeningocele, is a debilitating neural tube defect that affects patients and families throughout the world. Traditional management and treatment methods are described, followed by an explanation of why this is often ...
Burckart, Caryssa
core   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

The efficacy analysis of laparoscopic-assisted Soave procedure for Hirschsprung’s disease in neonates and infants within 3 months of age

Scientific Reports
To evaluate the efficacy of laparoscopic-assisted Soave procedure of Hirschsprung’s Disease (HSCR) in neonates and infants within 3 months of age. Patients with HSCR who were admitted to the Department of Fetal and Neonatal Surgery of Hunan Children’s ...
Renpeng Xia, Tidong Ma, Fan Zhao, Yong Xiao, Yong Feng, Ming Li, Chanjuan Zou, Guang Xu, Chonggao Zhou   +8 more
doaj   +1 more source

The method of hermetic sealing of iatrogenic damage of fetal membranes during fetal surgical interventions

Гинекология, 2018
The article presents a new method for treating iatrogenic damage to membranes in fetuscopic interventions. Since surgical treatment during pregnancy is associated with the use of trocar and amniotic fetal puncture, the most frequent complication of this ...
M.G.Shneyderman, T.Kh.Fatkhudinov, N.K.Tetruashvili, K.V.Kostyukov, V.A.Sakalo, I.V.Arutyunyan, K.A.Gladkova, R.G.Shmakov   +7 more
doaj   +1 more source